產(chǎn)品概述
ERCC1 Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,ICC/IF
Human,Mouse
產(chǎn)品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
ERCC1
ERCC1; DNA excision repair protein ERCC-1
2067
P07992
產(chǎn)品應(yīng)用
WB: 1:500-1:1000 IF: 1:50-1:200
Calculated MW: 33 kDa; Observed MW: 39 kDa
研究背景
DNA repair systems operate in all living cells to manage a variety of DNA lesions. Nucleotide excision repair (NER) is implemented in cases where bulky helix-distorting lesions occur, such as those brought about by UV and certain chemicals. Research studies have shown that expression of ERCC1 is related to survival rate and response to chemotherapeutic drugs in several human cancers including non-small cell lung cancer (NSCLC).
研究領(lǐng)域
Epigenetics and Nuclear Signaling
武漢恩璣生命科技有限公司
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