產(chǎn)品概述
ETAA1 Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB
Human
產(chǎn)品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
ETAA1
ETAA16
54465
Q9NY74
產(chǎn)品應(yīng)用
WB: 1:500-1:1000
Calculated MW: 103 kDa; Observed MW: 103 kDa
研究背景
Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1 (PubMed:27723720, PubMed:27723717). Probably only regulates a subset of ATR targets (PubMed:27723720, PubMed:27723717).
研究領(lǐng)域
Cancer
武漢恩璣生命科技有限公司
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