產(chǎn)品概述
PLK1 Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,ICC/IF,IP
Human,Rat
產(chǎn)品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
PLK1
PLK1; PLK; Serine/threonine-protein kinase PLK1; Polo-like kinase 1; PLK-1; Serine/threonine-protein kinase 13; STPK13
5347
P53350
產(chǎn)品應(yīng)用
WB: 1:500-1:1000 IF: 1:50-1:200 IP: 1:20
Calculated MW: 68 kDa; Observed MW: 68 kDa
研究背景
Required for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS.
研究領(lǐng)域
Cell Biology
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