產品概述
Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,IP
Human,Rat
產品性能
Unconjugated
Phosphorylated
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
MAPK1/MAPK3
5595/5594
P27361/P28482
產品應用
WB: 1:500-1:1000 IP: 1:20
Calculated MW: 44,42 kDa; Observed MW: 44,42 kDa
研究背景
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
研究領域
Neuroscience
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