產(chǎn)品概述
Nicastrin Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,IP
Human,Mouse,Rat
產(chǎn)品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
NCSTN
APH2; Ncstn; NCT; Nicastrin
23385
Q92542
產(chǎn)品應(yīng)用
WB: 1:500-1:1000 IP: 1:20
Calculated MW: 78 kDa; Observed MW: 110-120 kDa
研究背景
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
研究領(lǐng)域
Neuroscience
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