產(chǎn)品概述
Nibrin Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
WB,IHC-P,ICC/IF,FC,IP
Human,Mouse,Rat
產(chǎn)品性能
Unconjugated
Unmodified
IgG
Polyclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Affinity Chromatography
免疫原
NBN
NBN; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1
4683
O60934
產(chǎn)品應(yīng)用
WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 IP: 1:20 FC: 1:50-1:100
Calculated MW: 85 kDa; Observed MW: 95 kDa
研究背景
NBS1 is a member of the MRE11/RAD50 double-strand break repair complex. Involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. Mutation results in the Nijmegen breakage syndrome (NBS), an autosomal recessive chromosomal instability syndrome.
研究領(lǐng)域
Epigenetics and Nuclear Signaling
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