產(chǎn)品概述
Phospho-Src (Tyr419) Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
WB,FC
Human,Mouse,Rat
產(chǎn)品性能
Unconjugated
Phosphorylated
IgG
Polyclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Affinity Chromatography
免疫原
SRC
SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src
6714
P12931
產(chǎn)品應(yīng)用
WB: 1:500-1:1000 FC: 1:50-1:100
Calculated MW: 60 kDa; Observed MW: 60 kDa
研究背景
Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2).
研究領(lǐng)域
Signal Transduction
武漢恩璣生命科技有限公司
聯(lián)系商家時(shí)請(qǐng)?zhí)峒癱hemicalbook,有助于交易順利完成!
在線(xiàn)客服