| 價格 | 詢價 |
| 包裝 | 1支 |
| 最小起訂量 | 1支 |
| 發(fā)貨地 | 湖北 |
| 更新日期 | 2026-07-08 |
| 中文名稱:c-Myc (phospho Ser373)兔多抗 | 英文名稱:c-Myc (phospho Ser373) Rabbit Polyclonal Antibody |
| 品牌: EnkiLife | 產(chǎn)地: 中國 |
| 產(chǎn)品類別: 抗體 | |
| 是否進口: 否 | 用途: 科研 |
產(chǎn)品概述
產(chǎn)品性能
免疫原
產(chǎn)品應用
研究背景
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008],disease:A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with BTG1.,disease:Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors.,function:Participates in the regulation of gene transcription. Binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.,online information:Myc entry,PTM:Phosphorylated by PRKDC.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with TAF1C and SPAG9. Interacts with PARP10. Interacts with KDM5A and KDM5B.,
研究領域
Stem cell pathway; Cell_Cycle_G1S;Cell_Cycle_G2M_DNA; WNT;WNT-T CELL;β-Catenin; ErbB/HER; MAPK_ERK_Growth;MAPK_G_Protein; PI3K/Akt; Protein_Acetylation
| 成立日期 | 2024-08-02 (2年) | 注冊資本 | 271萬人民幣 |
| 員工人數(shù) | 10-50人 | 年營業(yè)額 | ¥ 100萬-300萬 |
| 主營行業(yè) | 生化試劑,抗體,細胞培養(yǎng),癌癥研究,細胞生物學 | 經(jīng)營模式 | 工廠,試劑,定制,服務 |
| 產(chǎn)品名稱 | 價格 | 公司名稱 | 報價日期 | |
|---|---|---|---|---|
| ¥1580 |
VIP4年
|
上海滬震實業(yè)有限公司
|
2026-07-28 | |
| ¥4543 |
武漢艾美捷科技有限公司
|
2026-07-12 | ||
| 詢價 |
VIP5年
|
上海優(yōu)寧維生物科技股份有限公司
|
2026-07-28 |