產(chǎn)品概述
| 產(chǎn)品名稱(Product Name) | Vimentin (phospho Ser83) Rabbit Polyclonal Antibody |
| 描述(Description) | Rabbit Polyclonal Antibody |
| 宿主(Host) | Rabbit |
| 應(yīng)用(Application) | WB,IHC-P,IF-P,IF-F,ICC/IF,ELISA |
| 種屬反應(yīng)性(Reactivity) | Human,Mouse,Rat |
產(chǎn)品性能
| 偶聯(lián)物(Conjugation) | Unconjugated |
| 修飾(Modification) | Phospho Antibody |
| 同種型(Isotype) | IgG |
| 克隆(Clonality) | Polyclonal |
| 形式(Form) | Liquid |
| 存放說(shuō)明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 儲(chǔ)存溶液(Buffer) | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N. |
| 純化方式(Purification) | Affinity purification |
免疫原
| 基因名(Gene Name) | VIM |
| 別名(Alternative Names) | VIM; Vimentin |
| 基因ID(Gene ID) | 7431 |
| 蛋白ID(SwissProt ID) | P08670 |
產(chǎn)品應(yīng)用
| 稀釋比(Dilution Ratio) | WB 1:500-1:2000, IHC-P 1:100-1:300, ELISA 1:10000, IF-P/IF-F/ICC/IF 1:50-200 |
| 蛋白分子量(Molecular Weight) | 54kDa |
研究背景
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009],function:Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.,online information:Vimentin entry,PTM:One of the most prominent phosphoproteins in various cells of mesenchymal origin. Phosphorylation is enhanced during cell division, at which time vimentin filaments are significantly reorganized.,sequence caution:Intron retention.,similarity:Belongs to the intermediate filament family.,subunit:Homopolymer. Interacts with HCV core protein. Interacts with LGSN and SYNM.,tissue specificity:Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.,
研究領(lǐng)域
關(guān)鍵字: VIM;Vimentin;(phospho;Ser83);Rabbit;Polyclonal;Antibody;一抗
武漢恩璣生命科技有限公司(EnkiLife)是一家深耕生命科學(xué),專注細(xì)胞生物學(xué)和免疫學(xué)科研試劑的研發(fā)、生產(chǎn)與銷售的生物技術(shù)企業(yè),在全球100多個(gè)國(guó)家和地區(qū)開(kāi)展業(yè)務(wù),致力于為科研工作者提供高質(zhì)量的產(chǎn)品和卓越的客戶服務(wù),推動(dòng)生命科學(xué)的發(fā)展。
EnkiLife的產(chǎn)品線涵蓋細(xì)胞系、原代細(xì)胞、細(xì)胞培養(yǎng)基、血清、細(xì)胞檢測(cè)試劑盒、重組靶點(diǎn)蛋白、細(xì)胞因子、重組抗體、ELISA試劑盒、生化試劑盒等,并提供技術(shù)服務(wù)與定制開(kāi)發(fā),覆蓋了生命科學(xué)研究的各大關(guān)鍵領(lǐng)域,包括細(xì)胞生物學(xué)、癌癥、免疫學(xué)、神經(jīng)科學(xué)、心血管疾病、干細(xì)胞、表觀遺傳學(xué)、內(nèi)分泌、蛋白質(zhì)組學(xué)、代謝組學(xué)等,全方位滿足您的實(shí)驗(yàn)需求,讓您享受科研的樂(lè)趣!
公司現(xiàn)已建立四大技術(shù)平臺(tái):
EnCyto?細(xì)胞培養(yǎng)及檢測(cè)平臺(tái):擁有細(xì)胞系庫(kù)(500+)、原代細(xì)胞庫(kù)(500+)、基礎(chǔ)培養(yǎng)基和完全培養(yǎng)基(1200+)
EnkiPro?重組蛋白平臺(tái):現(xiàn)貨產(chǎn)品2000+,可提供定制化表達(dá)服務(wù)
EnAb?重組抗體平臺(tái):重組兔單抗(3000+),可提供定制化和標(biāo)記服務(wù)
EnKits?試劑盒開(kāi)發(fā)平臺(tái):可提供優(yōu)質(zhì)的ELISA試劑盒、配套試劑、抗體對(duì)、生化試劑盒等相關(guān)產(chǎn)品
EnkiLife在生產(chǎn)管理方面引入ISO9001質(zhì)量管理體系和信息化、自動(dòng)化的管理工具,擁有高效穩(wěn)定的交付能力,與全球知名品牌建立了緊密的合作。
EnkiLife始終堅(jiān)持以技術(shù)創(chuàng)新為驅(qū)動(dòng),以匠心鑄就品質(zhì),以品質(zhì)服務(wù)客戶。
我們期待與更多的全球科研工作者和企業(yè)攜手合作,共同推動(dòng)生命科學(xué)領(lǐng)域的進(jìn)步與發(fā)展。