重組人BAFF (N-6His)蛋白,Recombinant Human BAFF (N-6His)

重組人BAFF (N-6His)蛋白 | EnkiLife恩璣生命

價格	詢價
包裝	1支

最小起訂量	1支
發(fā)貨地	湖北
更新日期	2026-07-08

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產(chǎn)品詳情

中文名稱:重組人BAFF (N-6His)蛋白	英文名稱:Recombinant Human BAFF (N-6His)
品牌: EnkiLife	產(chǎn)地: 中國
保存條件: Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.	產(chǎn)品類別: 重組蛋白
是否進口: 否	用途: 科研

產(chǎn)品名稱	Recombinant Human BAFF (N-6His)
英文名稱	BAFF/BLyS/TNFSF13B/TNFSF20/CD257
純度	Greater than 95% as determined by reducing SDS-PAGE
內(nèi)毒素	<1 EU/μg as determined by LAL test.
蛋白構建	Recombinant Human TNF Ligand Superfamily Member 13B is produced by our Mammalian expression system and the target gene encoding Ala134-Leu285 is expressed with a 6His tag at the N-terminus.
Accession	Q9Y275
表達宿主	Human Cells
種屬	Human
預測分子量	19.3 KDa
制劑	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
運輸方式	The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
穩(wěn)定性&儲存	Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
復溶	Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

分子別名

Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1

背景介紹

TNFSF13B/TNFSF20 belongs to the tumor necrosis factor family. It abundantly is expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas. Isoform 2 is expressed in many myeloid cell lines. Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. Isoform 2 seems to inhibit isoform 1 secretion and bioactivity. Isoform 3 acts as a transcription factor for its own parent gene, in association with NF-kappa-B p50 subunit, at least in autoimmune and proliferative B-cell diseases. The presence of Delta4BAFF is essential for soluble BAFF release by IFNG/IFN-gamma-stimulated monocytes and for B-cell survival. It can directly or indirectly regulate the differential expression of a large number of genes involved in the innate immune response and the regulation of apoptosis. Isoform 2 heteromultimerizes with isoform 1, probably limiting the amount of functional isoform 1 on the cell surface. Isoform 3 is unlikely form trimers or bind to BAFF receptors. Mature human BAFF consists of a 46 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 218 aa extracellular domain (ECD) with a stalk region and one TNF-like domain. Within aa 134-285 of the ECD, human BAFF shares 72% aa sequence identity with mouse BAFF.

注意事項

本司產(chǎn)品僅用于科研，不用于臨床診斷和治療

關鍵字： Recombinant;Human ;BAFF;protein

公司簡介

武漢恩璣生命科技有限公司（EnkiLife）是一家深耕生命科學，專注細胞生物學和免疫學科研試劑的研發(fā)、生產(chǎn)與銷售的生物技術企業(yè)，在全球100多個國家和地區(qū)開展業(yè)務，致力于為科研工作者提供高質(zhì)量的產(chǎn)品和卓越的客戶服務，推動生命科學的發(fā)展。 EnkiLife的產(chǎn)品線涵蓋細胞系、原代細胞、細胞培養(yǎng)基、血清、細胞檢測試劑盒、重組靶點蛋白、細胞因子、重組抗體、ELISA試劑盒、生化試劑盒等，并提供技術服務與定制開發(fā)，覆蓋了生命科學研究的各大關鍵領域，包括細胞生物學、癌癥、免疫學、神經(jīng)科學、心血管疾病、干細胞、表觀遺傳學、內(nèi)分泌、蛋白質(zhì)組學、代謝組學等，全方位滿足您的實驗需求，讓您享受科研的樂趣！公司現(xiàn)已建立四大技術平臺： EnCyto?細胞培養(yǎng)及檢測平臺：擁有細胞系庫（500+）、原代細胞庫（500+）、基礎培養(yǎng)基和完全培養(yǎng)基（1200+） EnkiPro?重組蛋白平臺：現(xiàn)貨產(chǎn)品2000+，可提供定制化表達服務 EnAb?重組抗體平臺：重組兔單抗（3000+），可提供定制化和標記服務 EnKits?試劑盒開發(fā)平臺：可提供優(yōu)質(zhì)的ELISA試劑盒、配套試劑、抗體對、生化試劑盒等相關產(chǎn)品 EnkiLife在生產(chǎn)管理方面引入ISO9001質(zhì)量管理體系和信息化、自動化的管理工具，擁有高效穩(wěn)定的交付能力，與全球知名品牌建立了緊密的合作。 EnkiLife始終堅持以技術創(chuàng)新為驅(qū)動，以匠心鑄就品質(zhì)，以品質(zhì)服務客戶。我們期待與更多的全球科研工作者和企業(yè)攜手合作，共同推動生命科學領域的進步與發(fā)展。

成立日期	2024-08-02 （2年）	注冊資本	271萬人民幣
員工人數(shù)	10-50人	年營業(yè)額	￥ 100萬-300萬
主營行業(yè)	生化試劑,抗體,細胞培養(yǎng),癌癥研究,細胞生物學	經(jīng)營模式	工廠,試劑,定制,服務

武漢恩璣生命科技有限公司

VIP 2年

公司成立：2年
注冊資本：271萬人民幣
企業(yè)類型：有限責任公司(自然人投資或控股)
主營產(chǎn)品：細胞系/原代細胞/培養(yǎng)基/基因編輯/功能檢測；重組蛋白/抗體；標記試劑盒；WB/IHC/TSA/ELISA試劑盒
公司地址：東湖新技術開發(fā)區(qū)高新大道666號C6棟

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