產(chǎn)品概述
AP-1 (phospho Thr239) Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
WB,IHC-P,IF-P,IF-F,ICC/IF,IP,ELISA
Human,Mouse,Rat
產(chǎn)品性能
Unconjugated
Phospho Antibody
IgG
Polyclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Affinity purification
免疫原
JUN
JUN; Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39
3725
P05412
產(chǎn)品應(yīng)用
WB 1:500-1:2000, IHC-P 1:100-1:300, Immunoprecipitation 2-5 ug/mg lysate, ELISA 1:20000, IF-P/IF-F/ICC/IF 1:50-200
39-42kDa
研究背景
This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008],function:Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.,PTM:Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Jun subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity). Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.,
研究領(lǐng)域
MAPK_ERK_Growth;MAPK_G_Protein;ErbB_HER;WNT;WNT-T CELLFocal adhesion;Toll_Like;T_Cell_Receptor;B_Cell_Antigen;Neurotrophin;GnRH;Epithelial cell signaling in Helicobacter pylori infection;Pathways in cancer;Colorectal cancer;Renal cell carcinoma;
武漢恩璣生命科技有限公司
聯(lián)系商家時(shí)請(qǐng)?zhí)峒癱hemicalbook,有助于交易順利完成!
在線客服