產(chǎn)品概述
| 產(chǎn)品名稱（Product Name） | CD151 Rabbit Polyclonal Antibody |
| 描述（Description） | Rabbit Polyclonal Antibody |
| 宿主（Host） | Rabbit |
| 應用（Application） | IHC-P,IF-P,IF-F,ICC/IF,ELISA |
| 種屬反應性（Reactivity） | Human,Mouse,Rat |
產(chǎn)品性能
| 偶聯(lián)物（Conjugation） | Unconjugated |
| 修飾（Modification） | Unmodified |
| 同種型（Isotype） | IgG |
| 克?。–lonality） | Polyclonal |
| 形式（Form） | Liquid |
| 存放說明（Storage） | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 儲存溶液（Buffer） | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N. |
| 純化方式（Purification） | Affinity purification |
免疫原
| 基因名（Gene Name） | CD151 TSPAN24 |
| 別名（Alternative Names） | CD151 antigen (GP27;Membrane glycoprotein SFA-1;Platelet-endothelial tetraspan antigen 3;PETA-3;Tetraspanin-24;Tspan-24;CD antigen CD151) |
| 基因ID（Gene ID） | 977 |
| 蛋白ID（SwissProt ID） | P48509 |
產(chǎn)品應用
| 稀釋比（Dilution Ratio） | IHC-P 1:50-200, ELISA 1:10000-20000, IF-P/IF-F/ICC/IF 1:50-200 |
| 蛋白分子量（Molecular Weight） | |
研究背景
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008],disease:Defects in CD151 are the cause of nephropathy with pretibial epidermolysis bullosa and deafness (NPEBD) [MIM:609057]. NPEBD is characterized by the association of hereditary nephritis, epidermolysis bullosa, deafness, and beta-thalassemia minor.,function:Essential for the proper assembly of the glomerular and tubular basement membranes in kidney.,induction:By HTLV-1.,online information:Blood group antigen gene mutation database,polymorphism:CD151 defines the MER2=RAPH1 antigen of the RAPH blood group system. 92% of Caucasians are MER2-positive and 8% are apparently MER2-negative.,similarity:Belongs to the tetraspanin (TM4SF) family.,subunit:Interacts with integrins alpha3beta1, alpha5beta1, alpha3beta1 and alpha6beta4, with CD9 and CD181.,tissue specificity:Expressed in a variety of tissues including vascular endothelium and epidermis. Expressed on erythroid cells, with a higher level of expression in erythroid precursors than on mature erythrocytes.,
研究領域
關鍵字： CD151 TSPAN24;CD151;Rabbit;Polyclonal;Antibody;一抗
武漢恩璣生命科技有限公司（EnkiLife）是一家深耕生命科學，專注細胞生物學和免疫學科研試劑的研發(fā)、生產(chǎn)與銷售的生物技術企業(yè)，在全球100多個國家和地區(qū)開展業(yè)務，致力于為科研工作者提供高質(zhì)量的產(chǎn)品和卓越的客戶服務，推動生命科學的發(fā)展。
EnkiLife的產(chǎn)品線涵蓋細胞系、原代細胞、細胞培養(yǎng)基、血清、細胞檢測試劑盒、重組靶點蛋白、細胞因子、重組抗體、ELISA試劑盒、生化試劑盒等，并提供技術服務與定制開發(fā)，覆蓋了生命科學研究的各大關鍵領域，包括細胞生物學、癌癥、免疫學、神經(jīng)科學、心血管疾病、干細胞、表觀遺傳學、內(nèi)分泌、蛋白質(zhì)組學、代謝組學等，全方位滿足您的實驗需求，讓您享受科研的樂趣！
公司現(xiàn)已建立四大技術平臺：
EnCyto?細胞培養(yǎng)及檢測平臺：擁有細胞系庫（500+）、原代細胞庫（500+）、基礎培養(yǎng)基和完全培養(yǎng)基（1200+）
EnkiPro?重組蛋白平臺：現(xiàn)貨產(chǎn)品2000+，可提供定制化表達服務
EnAb?重組抗體平臺：重組兔單抗（3000+），可提供定制化和標記服務
EnKits?試劑盒開發(fā)平臺：可提供優(yōu)質(zhì)的ELISA試劑盒、配套試劑、抗體對、生化試劑盒等相關產(chǎn)品
EnkiLife在生產(chǎn)管理方面引入ISO9001質(zhì)量管理體系和信息化、自動化的管理工具，擁有高效穩(wěn)定的交付能力，與全球知名品牌建立了緊密的合作。
EnkiLife始終堅持以技術創(chuàng)新為驅(qū)動，以匠心鑄就品質(zhì)，以品質(zhì)服務客戶。
我們期待與更多的全球科研工作者和企業(yè)攜手合作，共同推動生命科學領域的進步與發(fā)展。