產(chǎn)品概述
Napsin A Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
IHC-P,IF-P,IF-F,ICC/IF,ELISA
Human,Rat,Mouse
產(chǎn)品性能
Unconjugated
Unmodified
IgG
Polyclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Affinity purification
免疫原
NAPSA NAP1 NAPA
Napsin-A (EC 3.4.23.-;Aspartyl protease 4;ASP4;Asp 4;Napsin-1;TA01/TA02)
9476
O96009
產(chǎn)品應(yīng)用
IHC-P 1:50-200, ELISA 1:10000-20000, IF-P/IF-F/ICC/IF 1:50-200
研究背景
This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016],function:May be involved in processing of pneumocyte surfactant precursors.,similarity:Belongs to the peptidase A1 family.,tissue specificity:Expressed predominantly in adult lung (type II pneumocytes) and kidney and in fetal lung. Low levels in adult spleen and very low levels in peripheral blood leukocytes.,
研究領(lǐng)域
Lysosome;
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