Acetyl Hexapeptide-3 ( Argireline) is an amino-peptide developed to help reduce the appearance of fine lines and wrinkles. When applied to the skin of the face and neck, Acetyl Hexapeptide-3 helps to relax the muscles by temporarily limiting the overproduction and release of neurotransmitters that initiate and control the intensity of facial muscle contractions. When the muscles relax, the skin relaxes and flattens, reducing the appearance of wrinkles. Acetyl Hexapeptide-3 cosmetics have become a popular application for wrinkle treatment in USA and Europe for those averse to Botox Injection.