Product Name：Ganirelix
CAS No.：124904-93-4；123246-29-7（Hac）
Synonyms：醋酸加尼瑞克；Ganirelix acetate
Catalog No.：218P138
Brand：Typeptide Biotech（肽研生物）
Description：Ganirelix是一合成的與內(nèi)源性促性腺素釋放素（GnRH）（又稱促黃體生成素釋放素，LHRH）類似的十肽化合物，包含大量的非天然氨基酸，是GnRH的拮抗劑，其可競爭性拮抗促性腺的GnRH受體，從而變異途徑，引起快速、可逆性地抑制促性腺激素（黃體生成素LH和促卵泡激素FSH）分泌。 醋酸加尼瑞克抑制垂體分泌LH比抑制分泌FSH更顯著，從而降低性激素的產(chǎn)生。本公司生產(chǎn)的Ganirelix為研發(fā)級多肽，非最終成品。
Ganirelix is a synthetic decapeptide compound similar to endogenous gonadotropin-releasing hormone (GnRH) (also known as luteinizing hormone releasing hormone, LHRH), containing a large amount of non natural amino acids. It is an antagonist of GnRH and can competitively antagonize the GnRH receptor of gonadotropins, thereby mutating the pathway and causing rapid and reversible inhibition of gonadotropin (LH and FSH) secretion. Acetic acid induced ganciclovir inhibits pituitary secretion of LH more significantly than FSH secretion, thereby reducing the production of sex hormones. The Ganirelix produced by our company is a research grade peptide, not a final product.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Ac-D-Nal-[D-(PCL)Phe]-D-Pal-S-Y-D-Har(Et2)-L-Har(Et2)-P-d-A-NH2 |
Sequence(3-letter code) | Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-Tyr-D-Har(Et2)-Leu-Har(Et2)-Pro-D-Ala-NH2 |
Peptide Structure | 
|
Molecular Formula | C80H113ClN18O13 |
Molecular Weight | 1570.35 |
訂購聯(lián)系方式：
南京肽研生物生物科技有限公司
手機號：19961912513(微信同號)
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用，不得用于人體。
關(guān)鍵字： Ganirelix;Ganirelix acetate;醋酸加尼瑞克;123246-29-7（Hac）;124904-93-4;
肽研生物坐落于國家級新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠信、嚴 謹、務(wù)實”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類型和優(yōu)質(zhì)的產(chǎn)品。