Product Name：WLBU2
CAS No.：847061-43-2
Synonyms：工程陽離子抗菌肽WLBU2
Catalog No.：220P284
Brand：Typeptide Biotech（肽研生物）
Description：WLBU2 是一種工程陽離子抗菌肽 (eCAP)，是由24個(gè)氨基酸組成的多肽，可克服天然抗菌肽 (AMPs) 在環(huán)境中的敏感性問題。WLBU2 表現(xiàn)出快速殺菌作用，對(duì)多種革蘭氏陽性菌和陰性菌的 MIC 值 ≤ l0 μM (包括耐甲氧西林金黃色葡萄球菌、耐萬古霉素腸球菌、肺炎克雷伯菌、產(chǎn)氣腸桿菌、陰溝腸桿菌、大腸埃希菌等)。 WLBU2 能阻止銅綠假單胞菌的生物膜生長(zhǎng)，在富含粘液、低 pH 和高鹽濃度的環(huán)境仍能保持活性，且對(duì)人類呼吸道上皮細(xì)胞無不良影響。WLBU2 可用于研究囊性纖維化 (CF) 與銅綠假單胞菌感染。
WLBU2 is an engineered cationic antimicrobial peptide (eCAP) composed of 24 amino acids, which overcomes the sensitivity issue of natural antimicrobial peptides (AMPs) in the environment. WLBU2 exhibits rapid bactericidal activity, with MIC values ≤ 10 μ M against various Gram positive and Gram negative bacteria (including methicillin-resistant Staphylococcus aureus, vancomycin resistant Enterococcus, Klebsiella pneumoniae, Enterobacter aerogenes, Enterobacter cloacae, Escherichia coli, etc.). WLBU2 can prevent the biofilm growth of Pseudomonas aeruginosa, maintain activity in environments rich in mucus, low pH, and high salt concentration, and has no adverse effects on human respiratory epithelial cells. WLBU2 can be used to study cystic fibrosis (CF) and Pseudomonas aeruginosa infection.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | RRWVRRVRRWVRRVVRVVRRWVRR |
Sequence(3-letter code) | H-Arg-Arg-Trp-Val-Arg-Arg-Val-Arg-Arg-Trp-Val-Arg-Arg-Val-Val-Arg-Val-Val-Arg-Arg-Trp-Val-Arg-Arg-OH |
Peptide Structure | 
|
Molecular Formula | C151H260N66O25 |
Molecular Weight | 3400.11 |
訂購(gòu)聯(lián)系方式：
南京肽研生物生物科技有限公司
手機(jī)號(hào)：19961912513(微信同號(hào))
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用，不得用于人體。
關(guān)鍵字： WLBU2;工程陽離子抗菌肽WLBU2;847061-43-2;多肽;多肽合成;
肽研生物坐落于國(guó)家級(jí)新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠(chéng)信、嚴(yán) 謹(jǐn)、務(wù)實(shí)”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類型和優(yōu)質(zhì)的產(chǎn)品。