Product Description
(S)-2-[(S)-2-Amino-2-(tetrahydrofuran-3-yl)acetamido]-2-(tetrahydrofuran-3-yl)acetic Acid is a highly functionalized chiral amino acid building block designed for peptide chemistry and medicinal chemistry applications.
Featuring two stereochemically defined tetrahydrofuran-containing amino acid units, this compound provides a rigid three-dimensional scaffold that can enhance conformational control, improve molecular recognition, and expand chemical diversity during lead optimization. Its multiple functional groups make it suitable for peptide elongation, analogue synthesis, and structure–activity relationship (SAR) studies.
This building block is particularly valuable for the development of peptide therapeutics, macrocycles, enzyme inhibitors, and other biologically active small molecules.
Key Features
Chiral amino acid building block
Dual tetrahydrofuran (THF) motifs
Conformationally constrained scaffold
Suitable for peptide synthesis and medicinal chemistry
Ideal for SAR studies and analogue library construction
Available for custom synthesis and scale-up
中文產(chǎn)品描述
(S)-2-[(S)-2-氨基-2-(四氫呋喃-3-基)乙酰氨基]-2-(四氫呋喃-3-基)乙酸 是一種具有多個(gè)手性中心的高級(jí)氨基酸砌塊，適用于多肽化學(xué)、藥物化學(xué)及創(chuàng)新藥研發(fā)。
該化合物含有兩個(gè) 四氫呋喃（THF） 手性單元，可提供剛性的三維空間構(gòu)象，有助于提高分子識(shí)別能力，并豐富先導(dǎo)化合物的結(jié)構(gòu)多樣性。其兼具氨基和羧基等活性官能團(tuán)，可廣泛用于多肽延伸、類(lèi)似物合成以及構(gòu)效關(guān)系（SAR）研究。
Applications
關(guān)鍵字： Amino acid;Chiral;Pharmaceutical inter;Custom synthesis;
**重慶速研醫(yī)藥科技有限公司（Chongqing Rapidsyn Pharmaceutical Technology Co., Ltd.）** 是一家專(zhuān)注于醫(yī)藥化學(xué)研發(fā)和定制合成服務(wù)的高新技術(shù)企業(yè)。公司擁有經(jīng)驗(yàn)豐富的研發(fā)團(tuán)隊(duì)，可提供從毫克（mg）到公斤（kg）級(jí)別的定制合成、工藝開(kāi)發(fā)、藥物中間體及科研化學(xué)品開(kāi)發(fā)服務(wù)。
依托專(zhuān)業(yè)的技術(shù)能力、嚴(yán)格的質(zhì)量控制和高效的項(xiàng)目管理，重慶速研致力于為全球制藥企業(yè)、生物技術(shù)公司、高校及科研機(jī)構(gòu)提供可靠、高效的化學(xué)研發(fā)解決方案，幫助客戶(hù)加速研發(fā)進(jìn)程。