Product Name： CPI1
CAS No.：3085809-95-3
Synonyms：抑制劑多肽多肽CPI1
Catalog No.：220P289
Brand：Typeptide Biotech（肽研生物）
Description：CPI1 是一種有效的且高特異性的多藥耐藥蛋白 1 (MRP1) 抑制劑多肽，是由17個氨基酸組成的脂鍵環(huán)肽。CPI1 對 MRP1 具有納摩爾級的抑制活性 (Ki: 100 nM)，對 P-糖蛋白 (Pgp) 的抑制作用很小。CPI1 與 LTC4 競爭結(jié)合 MRP1 的同一位點，抑制 ATP 水解和底物轉(zhuǎn)運。CPI1 可用于藥物遞送和癌癥化療耐藥性的研究。
CPI1 is a potent and highly specific peptide inhibitor of multidrug resistance protein 1 (MRP1), consisting of a 17-amino acid lipopeptide with a cyclic structure. CPI1 exhibits nanomolar-level inhibitory activity against MRP1 (Ki: 100 nM) with minimal effect on P-glycoprotein (Pgp). CPI1 competes with LTC4 for binding to the same site of MRP1, inhibiting ATP hydrolysis and substrate transport. CPI1 can be utilized in drug delivery and research on chemotherapy resistance in cancer.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Ac-{d-Tyr}-FWGNLHWYYEQFDSTC(Thioether bond between: Ac-d-Tyr1-Cys15) |
Sequence(3-letter code) | Ac-{d-Tyr}-Phe-Trp-Gly-Asn-Leu-His-Trp-Tyr-Tyr-Glu-Gln-Phe-Asp-Ser-Thr-Cys-OH(Thioether bond between: Ac-d-Tyr1-Cys15) |
Peptide Structure | 
|
Molecular Formula | C111H131N23O30S1 |
Molecular Weight | 2299.43 |
訂購聯(lián)系方式：
南京肽研生物生物科技有限公司
手機(jī)號：19961912513(微信同號)
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用，不得用于人體。
關(guān)鍵字： 抑制劑多肽多肽CPI1;3085809-95-3;CPI1;多肽;多肽合成;
肽研生物坐落于國家級新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠信、嚴(yán) 謹(jǐn)、務(wù)實”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類型和優(yōu)質(zhì)的產(chǎn)品。