Product Name： Alloferon
CAS No.：347884-61-1
Synonyms：Alloferon 1；Antimicrobial peptide；麗蠅抗病毒肽1
Catalog No.：218P378
Brand：Typeptide Biotech（肽研生物）
Description：Alloferon是一類從細(xì)菌感染的果蠅分離得到的十三肽，具有抗腫瘤、抗病毒、抗炎癥、免疫調(diào)控的多重生物活性，其發(fā)揮作用的機(jī)理類似免疫調(diào)節(jié)肽，通過激發(fā)機(jī)體自然殺傷細(xì)胞NK的細(xì)胞毒殺作用及促進(jìn)干擾素INF-α來發(fā)揮其生物活性。2003年，Alloferon成功在俄羅斯上市，臨床適應(yīng)癥為女性人乳頭瘤病毒HPV感染。鑒于Alloferon的獨(dú)特優(yōu)勢，如無細(xì)胞毒性、無免疫原性、無突變或致癌效應(yīng)、無胚胎毒性、無生殖毒性，對于其衍生物的研究將為創(chuàng)造出更高效、安全的抗菌肽AMP、抗腫瘤多肽ACP。
Alloferon is a class of tridecapeptides isolated from bacteria-infected fruit flies, exhibiting multiple biological activities such as antitumor, antiviral, anti-inflammatory, and immunomodulatory effects. Its mechanism of action resembles that of immunomodulatory peptides, functioning by stimulating the cytotoxic activity of natural killer (NK) cells and promoting interferon INF-α to exert its biological effects. In 2003, Alloferon was successfully marketed in Russia, with clinical indications for female human papillomavirus (HPV) infection. Given Alloferon's unique advantages, such as non-cytotoxicity, non-immunogenicity, absence of mutagenic or carcinogenic effects, embryotoxicity, and reproductive toxicity, research on its derivatives will contribute to the development of more efficient and safer antimicrobial peptides (AMPs) and antitumor polypeptides (ACPs).
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | HGVSGHGQHGVHG |
Sequence(3-letter code) | H-His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly-OH |
Peptide Structure | 
|
Molecular Formula | C52H76N22O16 |
Molecular Weight | 1265.32 |
訂購聯(lián)系方式：
南京肽研生物生物科技有限公司
手機(jī)號：19961912513(微信同號)
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用，不得用于人體。
關(guān)鍵字： Alloferon;麗蠅抗病毒肽1;347884-61-1;多肽;多肽合成;
肽研生物坐落于國家級新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠信、嚴(yán) 謹(jǐn)、務(wù)實(shí)”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類型和優(yōu)質(zhì)的產(chǎn)品。