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Chromogranin A 抗體

品牌：MedChemExpress (MCE)

貨號(hào)：HY-P85880

存儲(chǔ)條件：-20°C保存1年。避免重復(fù)凍結(jié)/解凍循環(huán)。

運(yùn)輸條件：用藍(lán)冰運(yùn)輸。

產(chǎn)品活性：Chromogranin A Antibody (YA5572) 是一種小鼠來(lái)源、無(wú)偶聯(lián)標(biāo)記、抗 Chromogranin A 的 IgG 單克隆抗體。它可用于人、小鼠、大鼠、背景下的 IHC-P、WB、ICC/IF、ELISA 實(shí)驗(yàn)。

研究背景：CHGA 蛋白對(duì)葡萄糖誘導(dǎo)的胰腺胰島素釋放具有強(qiáng)烈的抑制作用。它作為非競(jìng)爭(zhēng)性煙堿膽堿能拮抗劑，抑制嗜鉻細(xì)胞和去甲腎上腺素能神經(jīng)元釋放兒茶酚胺。此外，CHGA 對(duì)革蘭氏陽(yáng)性菌（金黃色葡萄球菌和藤黃桿菌）和革蘭氏陰性菌（大腸桿菌和銅綠假單胞菌）均具有抗菌活性。此外，它具有誘導(dǎo)肥大細(xì)胞遷移、脫顆粒以及細(xì)胞因子和趨化因子產(chǎn)生的能力。此外，CHGA 在體外可作為自由基的有效清除劑，并可能在調(diào)節(jié)心臟功能和血壓中發(fā)揮作用。

宿主：Mouse

反應(yīng)物種：Human, Mouse, Rat

推薦稀釋比例：IHC: 1:200-1000; WB: 1:500-2000; ICC/IF: 1:100-500; ELISA: 1:1000-5000 Immunohistochemical analysis of paraffin-embedded rat pancreas tissue using Chromogranin A (PTR1330) Antibody. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX. Immunohistochemical analysis of paraffin-embedded rat pancreas tissue using Chromogranin A (PTR1330) Antibody. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

基因 ID：1113

同用名：beta Granin antibody; betagranin; N-terminal fragment of chromogranin A; antibody; catestatin antibody; CgA antibody; CHG A antibody; Chga antibody; chromofungin antibody; Chromogranin A antibody; Chromogranin A parathyroid secretory protein 1 antibody; Chromogranin A precursor antibody; ChromograninA antibody; CMGA_HUMAN antibody; ER-37 antibody; Pancreastatin antibody; Parastatin antibody; Parathyroid secretory protein 1 antibody; Pituitary secretory protein I antibody; Secretory protein I antibody; SP I antibody; SP-I antibody; SP1 antibody; SPI antibody; vasostatin 2 antibody; Vasostatin antibody; Vasostatin I antibody; Vasostatin II antibody; vasostatin-2 antibody;

克隆性：Monoclonal

偶聯(lián)：Non-conjugated

修飾：Unmodified

蛋白數(shù)據(jù)庫(kù)：P10645

同型：IgG

詳情參考：www.medchemexpress.cn/antibody/chromogranin-a-antibody-ya5572.html