貨號(hào)：GS40482

Oberotatug is a humanized IgG1?kappa monoclonal antibody that specifically targets LY75, also known as CD205 or DEC?205, a type I transmembrane C?type lectin receptor. As an IgG1 isotype, it is designed to engage immune effector functions such as antibody?dependent cellular cytotoxicity (ADCC). DEC?205 is primarily expressed on dendritic cells (DCs) and some other antigen?presenting cells, where it plays a key role in antigen uptake and presentation. By binding to DEC?205, oberotatug may modulate dendritic cell function or serve as a vehicle to deliver antigens or therapeutic payloads specifically to these cells. It is being developed as a potential immunomodulatory agent for cancer immunotherapy or vaccine enhancement.