貨號(hào)：GS40524

Ozuriftamab is a humanized IgG1?kappa monoclonal antibody that targets receptor tyrosine kinase?like orphan receptor 2 (ROR2), a transmembrane receptor belonging to the ROR family of receptor tyrosine kinases. As an IgG1 isotype, it is designed to engage immune effector functions such as antibody?dependent cellular cytotoxicity (ADCC). ROR2 is involved in developmental signaling pathways (e.g., Wnt/planar cell polarity) and is often overexpressed in certain cancers, where it may promote tumor progression, metastasis, and treatment resistance.