Product Name：α-Conotoxin SIA
CAS No.：135190-31-7
Synonyms：α-芋螺毒素 SIA
Catalog No.：218P036
Brand：Typeptide Biotech（肽研生物）
Description：α-Conotoxin SIA是SIA型α-芋螺毒素系列中的一種序列，由13個(gè)氨基酸組成，結(jié)構(gòu)中含有兩對(duì)二硫鍵。α-Conotoxin SIA是一種對(duì)肌肉nAChR具有高親和力的選擇性煙堿乙酰膽堿受體（nAChR拮抗劑多肽，α-Conotoxin SIA優(yōu)先靶向小鼠肌肉nAChR的α/δ界面。相比之下，對(duì)于魚(yú)雷nAChR，α-Conotoxin SIA對(duì)α/γ的親和力遠(yuǎn)高于α/δ界面的親和力。
α-Conotoxin SIA is a sequence in the SIA type alpha conotoxin series, consisting of 13 amino acids and containing two pairs of disulfide bonds in its structure. α-Conotoxin SIA is a selective nicotinic acetylcholine receptor (nAChR antagonist peptide) with high affinity for muscle nAChR. α-Conotoxin SIA preferentially targets the alpha/delta interface of mouse muscle nAChR. In contrast, for torpedo nAChR, the affinity of α - Coronation SIA for α/γ is much higher than the affinity for the α/δ interface.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | YCCHPACGKNFDC-NH2(Disulfide bridge：Cys2-Cys7;Cys3-Cys13) |
Sequence(3-letter code) | H-Tyr-Cys-Cys-His-Pro-Ala-Cys-Gly-Lys-Asn-Phe-Asp-Cys-NH2(Disulfide bridge: Cys2-Cys7,Cys3-Cys13) |
Peptide Structure | 
|
Molecular Formula | C60H82N18O17S4 |
Molecular Weight | 1455.66 |
訂購(gòu)聯(lián)系方式：
南京肽研生物生物科技有限公司
手機(jī)號(hào)：19961912513(微信同號(hào))
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用，不得用于人體。
關(guān)鍵字： α-Conotoxin SIA;α-芋螺毒素 SIA;135190-31-7;多肽;多肽合成;
肽研生物坐落于國(guó)家級(jí)新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠(chéng)信、嚴(yán) 謹(jǐn)、務(wù)實(shí)”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類型和優(yōu)質(zhì)的產(chǎn)品。