Product Name：Senktide
CAS No.：106128-89-6
Synonyms：速激肽NK-3受體激動(dòng)劑多肽Senktide
Catalog No.：207P23
Brand：Typeptide Biotech（肽研生物）
Description：Senktide顯示出選擇性地與速激肽受體亞型(SP-N)相互作用，可用于研究以找出該受體的調(diào)節(jié)、分布和功能作用。Senktide是速激肽NK-3受體激動(dòng)劑多肽，序列中包含6個(gè)氨基酸，且有一個(gè)非天然氨基酸，可能會(huì)導(dǎo)致類似于小鼠模型中血清素刺激的行為。已注意到 NK-3R（速激肽 NK-3 受體）可介導(dǎo)豚鼠肺中的支氣管收縮，并且Senktide對(duì)這些受體的激活也已顯示可誘導(dǎo)支氣管收縮。 此外，Senktide已證明能夠在豚鼠大腦的許多區(qū)域誘導(dǎo)更多數(shù)量的Fos-LI神經(jīng)元。
Senktide selectively interacts with the substance P receptor subtype (SP-N) and can be used to study the regulation, distribution, and functional roles of this receptor. Senktide is a peptide agonist of the substance P NK-3 receptor, containing six amino acids with one unnatural amino acid, which may lead to behavioral effects similar to those induced by serotonin stimulation in mouse models. It has been noted that the NK-3R (substance P NK-3 receptor) mediates bronchoconstriction in guinea pig lungs, and activation of these receptors by Senktide has also been shown to induce bronchoconstriction. Additionally, Senktide has been demonstrated to induce a higher number of Fos-LI neurons in various regions of the guinea pig brain.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Suc-DF-(N-me-Phe)-GLM-NH2 |
Sequence(3-letter code) | Suc-Asp-Phe-(N-me-Phe)-Gly-Leu-Met-NH2 |
Peptide Structure | 
|
Molecular Formula | C40H55N7O11S1 |
Molecular Weight | 841.97 |
訂購(gòu)聯(lián)系方式：
南京肽研生物生物科技有限公司
手機(jī)號(hào)：19961912513(微信同號(hào))
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用，不得用于人體。
關(guān)鍵字： Senktide;速激肽NK-3受體激動(dòng)劑多肽Senkti;106128-89-6;多肽;多肽合成;
肽研生物坐落于國(guó)家級(jí)新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠(chéng)信、嚴(yán) 謹(jǐn)、務(wù)實(shí)”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類型和優(yōu)質(zhì)的產(chǎn)品。