Product Name：Connexin mimetic peptide 40,37GAP26
CAS No.： 514787-21-4
Synonyms：血管連接蛋白 (Cx37、Cx40) 胞外環(huán)多肽
Catalog No.：218P989
Brand：Typeptide Biotech（肽研生物）
Description：Connexin mimetic peptide 40,37GAP26是由13個(gè)氨基酸組成的多肽，Connexin mimetic peptide 40,37GAP26對(duì)應(yīng)于主要血管連接蛋白 (Cx37、Cx40) 胞外環(huán)的 GAP26 結(jié)構(gòu)域，根據(jù) Cx 同源性指定為 37、40Gap 26。Connexin mimetic peptide 40,37GAP26用于研究間隙連接在環(huán)吡嗪酸 (CPA) 穿過嚙齒動(dòng)物髂動(dòng)脈壁引起的內(nèi)皮超極化擴(kuò)散中的作用。由 Cx37 和 Cx40 構(gòu)建的間隙連接斑塊在內(nèi)皮細(xì)胞中含量豐富。Connexin mimetic peptide 40,37GAP26對(duì)內(nèi)膜下超極化具有抑制作用。
Connexin mimetic peptide 40,37GAP26 is a peptide composed of 13 amino acids. Connexin mimetic peptide 40,37GAP26 corresponds to the GAP26 domain of the extracellular loop of major vascular junction proteins (Cx37, Cx40), designated as 37,40Cap 26 based on Cx homology. Connexin mimetic peptide 40,37GAP26 was used to investigate the role of gap junctions in endothelial hyperpolarization diffusion induced by cyclic pyrazine acid (CPA) passing through the iliac artery wall of rodents. The gap junction plaques constructed by Cx37 and Cx40 are abundant in endothelial cells. Connexin mimetic peptide 40,37GAP26 has inhibitory effects on subendothelial hyperpolarization.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | VCYDQAFPISHIR |
Sequence(3-letter code) | H-Val-Cys-Tyr-Asp-Gln-Ala-Phe-Pro-Ile-Ser-His-Ile-Arg-OH |
Peptide Structure | 
|
Molecular Formula | C70H105N19O19S1 |
Molecular Weight | 1548.76 |
訂購聯(lián)系方式：
南京肽研生物生物科技有限公司
手機(jī)號(hào)：19961912513(微信同號(hào))
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用，不得用于人體。
關(guān)鍵字： Connexin mimetic pep;血管連接蛋白 (Cx37、Cx40) 胞;514787-21-4;多肽;多肽合成;
肽研生物坐落于國家級(jí)新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠信、嚴(yán) 謹(jǐn)、務(wù)實(shí)”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類型和優(yōu)質(zhì)的產(chǎn)品。