Product Name：Cotadutide acetate
CAS No.：1686108-82-6
Synonyms：雙重肽激動劑多肽Cotadutide；MEDI0382 acetate
Catalog No.：218P269
Brand：Typeptide Biotech（肽研生物）
Description：Cotadutide acetate是胰高血糖素樣肽-1 (GLP-1)和胰高血糖素受體 (glucagon receptor) 的有效雙重肽激動劑多肽，序列中含有31個氨基酸，多肽的N端由棕櫚酸封閉，多肽結構中含有一個酰胺鍵組成的環(huán)狀結構，EC50 值分別為 6.9 pM 和 10.2 pM。Cotadutide acetate有促進減肥和控制血糖的能力，有潛力用于肥胖癥和 2 型糖尿病 (T2D) 的研究。
Cotadutide acetate is a potent dual peptide agonist targeting both glucagon-like peptide-1 (GLP-1) and glucagon receptors, consisting of 31 amino acids in its sequence. The N-terminus of the peptide is blocked by palmitic acid, and its structure contains a cyclic configuration formed by an amide bond. The EC50 values are 6.9 pM and 10.2 pM, respectively. Cotadutide acetate possesses the ability to promote weight loss and regulate blood glucose, showing potential for research in obesity and type 2 diabetes (T2D).
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | HSQGTFTSDK（γ-E-Plam）SEYLDSERARDFVAWLEAGG |
Sequence(3-letter code) | H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Lys（γ-Glu-Plam）-Ser-Glu-Tyr-Leu-Asp-Ser-Glu-Arg-Ala-Arg-Asp-Phe-Val-Ala-Trp-Leu-Glu-Ala-Gly-Gly-OH |
Peptide Structure | 
|
Molecular Formula | C167H252N42O55 |
Molecular Weight | 3728.09 |
訂購聯系方式：
南京肽研生物生物科技有限公司
手機號：19961912513(微信同號)
QQ: 2178255659
郵箱：sales@typeptide.com
聯系人：顧經理
申明：本產品僅供科研使用，不得用于人體。
關鍵字： Cotadutide acetate;雙重肽激動劑多肽Cotadutide；M;1686108-82-6;多肽;多肽合成;
肽研生物坐落于國家級新區(qū)南京江北新區(qū)新材料產業(yè)園，是一家專業(yè)從事多肽產 品的研發(fā)、生產和銷售以及多肽技術轉讓的高新技術企業(yè)。公司秉持“誠信、嚴 謹、務實”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類型和優(yōu)質的產品。