Product Name：c(RGDfV)
CAS No.：137813-35-5
Synonyms：細(xì)胞粘附抑制劑多肽cyclo (Arg-Gly-Asp-d-Phe-Val)
Catalog No.：143P24
Brand：Typeptide Biotech（肽研生物）
Description：c(RGDfV)是一種有效的細(xì)胞粘附抑制劑，是由5個(gè)氨基酸組成的環(huán)狀多肽，可抑制腫瘤細(xì)胞對(duì)層粘連蛋白和玻連蛋白底物的粘附。大鼠體內(nèi)的研究提供了其在改善缺血性急性腎功能衰竭中的效用的第一個(gè)證據(jù)。c(RGDfV) 還通過(guò)阻止細(xì)胞間粘附來(lái)抑制腎小管阻塞，還有實(shí)驗(yàn)表明環(huán)肽c(RGDfV)還可用于預(yù)防視網(wǎng)膜新生血管形成；其次，c(RGDfV) 與avb3受體結(jié)合。
c(RGDfV) is an effective cell adhesion inhibitor, a cyclic peptide composed of five amino acids that inhibits tumor cell adhesion to laminin and vitronectin substrates. Studies in rats provided the first evidence of its utility in improving ischemic acute renal failure. c(RGDfV) also inhibits renal tubular obstruction by blocking intercellular adhesion, and experiments have shown that the cyclic peptide c(RGDfV) can also be used to prevent retinal neovascularization. Additionally, c(RGDfV) binds to the avb3 receptor.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | cyclo(RGDfV) |
Sequence(3-letter code) | cyclo (Arg-Gly-Asp-d-Phe-Val) |
Peptide Structure | 
|
Molecular Formula | C26H38N8O7 |
Molecular Weight | 574.63 |
訂購(gòu)聯(lián)系方式：
南京肽研生物生物科技有限公司
手機(jī)號(hào)：19961912513(微信同號(hào))
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用，不得用于人體。
關(guān)鍵字： 細(xì)胞粘附抑制劑多肽cyclo (Arg-;137813-35-5;c(RGDfV);多肽;多肽合成;
肽研生物坐落于國(guó)家級(jí)新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專(zhuān)業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷(xiāo)售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠(chéng)信、嚴(yán) 謹(jǐn)、務(wù)實(shí)”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類(lèi)型和優(yōu)質(zhì)的產(chǎn)品。