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Lyn A, Human, 重組蛋白 (GST),Lyn A Protein, Human, Recombinant (GST)
  • Lyn A, Human, 重組蛋白 (GST),Lyn A Protein, Human, Recombinant (GST)

Lyn A, Human, 重組蛋白 (GST)|TMPY-04391|TargetMol

價格 585
包裝 5μg
最小起訂量 5μg
發(fā)貨地 上海
更新日期 2026-05-08
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產(chǎn)品詳情

中文名稱:Lyn A, Human, 重組蛋白 (GST)英文名稱:Lyn A Protein, Human, Recombinant (GST)
品牌: TargetMol產(chǎn)地: 美國
保存條件: Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months產(chǎn)品類別: 抑制劑
種屬: Human表達(dá)系統(tǒng): Baculovirus Insect Cells
蛋白長度: A DNA sequence encoding the human LYN isoform a (NP_002341.1) (Met 1-Pro 512) was fused with the GST tag at the N-terminus. Predicted N terminal: Met標(biāo)簽: N-GST
貨號: T011|TMPY-04391
2026-05-08 Lyn A, Human, 重組蛋白 (GST) Lyn A Protein, Human, Recombinant (GST) 5μg/585RMB 585 TargetMol 美國 Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months 抑制劑

Product Introduction

Bioactivity

名稱Lyn A Protein, Human, Recombinant (GST)
描述Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many functions. Lyn kinase may downregulate the expression of stem cell growth factor receptor (KIT). Lyn kinase Acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between proliferation and maturation. Lyn kinase also acts as a positive regulator of cell movement while negatively regulating adhesion to stromal cells by inhibiting the ICAM-1-binding activity of beta-2 integrins. Lyn kinase relays suppressing signals from the chemokine receptor CXCR4 to beta-2 integrin LFA-1 in hematopoietic precursors. This kinase is involved in the induction of stress-activated protein kinase (SAPK), but not ERK or p38 MAPK, in response to genotoxic agents. In a word, Lyn kinase functions primarily as a negative regulator, but can also function as an activator, depending on the context. Tyrosine-protein kinase Lyn is Required for the initiation of the B-cell response, but also its down-regulation and termination. It also plays an important role in the regulation of B-cell differentiation, proliferation, survival, and apoptosis, and is important for immune self-tolerance. It has been reported that Lyn kinase plays a role in the inflammatory response to bacterial lipopolysaccharide. Lyn kinase Mediates the responses to cytokines and growth factors in hematopoietic progenitors, platelets, erythrocytes, and in mature myeloid cells, such as dendritic cells, neutrophils, and eosinophils.
存儲條件Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
關(guān)鍵字JTK-8 | JTK 8
關(guān)鍵字: p56Lyn;p53Lyn;LYN proto-oncogene, Src family tyrosine kinase;JTK8;TargetMol

公司簡介

成立日期 2013-04-18 (14年) 注冊資本 589.8595萬人民幣
員工人數(shù) 100-500人 年?duì)I業(yè)額 ¥ 1億以上
主營行業(yè) 天然產(chǎn)物,生物化工,化學(xué)試劑,生物技術(shù)服務(wù) 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • TargetMol 中國(陶術(shù)生物)
VIP 1年
  • 公司成立:14年
  • 注冊資本:589.8595萬人民幣
  • 企業(yè)類型:股份有限公司(非上市、自然人投資或控股)
  • 主營產(chǎn)品:活性分子、生化試劑、天然產(chǎn)物、重組蛋白、抗體相關(guān)、試劑盒、藥物篩選化合物庫、技術(shù)服務(wù)
  • 公司地址:靜安區(qū)江場三路238號8樓
詢盤

Lyn A, Human, 重組蛋白 (GST)|TMPY-04391|TargetMol相關(guān)廠家報(bào)價

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