| 價(jià)格 | ¥1350 |
| 包裝 | 20μg |
| 最小起訂量 | 20μg |
| 發(fā)貨地 | 上海 |
| 更新日期 | 2026-05-08 |
| 中文名稱:BMP5, Human, 重組蛋白 (hFc) | 英文名稱:BMP-5 Protein, Human, Recombinant (hFc) |
| 品牌: TargetMol | 產(chǎn)地: 美國 |
| 保存條件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months | 產(chǎn)品類別: 抑制劑 |
| 種屬: Human | 表達(dá)系統(tǒng): HEK293 Cells |
| 蛋白長度: A DNA sequence encoding the carboxy-terminal domain (Gln 324-His 454) (the mature chain) of human BMP5 (NP_066551.1) was expressed with the fused Fc region of human IgG1 at the N-terminus. Predicted N terminal: Glu 20 | 標(biāo)簽: N-hFc |
| 貨號(hào): T011|TMPY-00681 |
| 名稱 | BMP-5 Protein, Human, Recombinant (hFc) |
| 描述 | Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily. In agreement with a possible role in the control of cell death, BMP-5 exhibited a regulated pattern of expression in the interdigital tissue. Transcripts of BMP-5 and BMP-5 protein were abundant within the cytoplasm of the fragmenting apoptotic interdigital cells in a way suggesting that delivery of BMPs into the tissue is potentiated during apoptosis. Gain-of-function experiments demonstrated that BMP-5 has the same effect as other interdigital BMPs inducing apoptosis in the undifferentiated mesoderm and growth in the prechondrogenic mesenchyme. BMP-5 is a member of the 60A subgroup of BMPs, other members of which have been shown to stimulate dendritic growth in central and peripheral neurons. The signaling pathway that mediates the dendrite-promoting activity of BMP-5 may involve binding to BMPR-IA and activation of Smad-1, and relative levels of BMP antagonists such as noggin and follistatin may modulate BMP-5 signaling. Since BMP-5 is expressed at relatively high levels not only in the developing but also the adult nervous system, these findings suggest the possibility that BMP-5 regulates dendritic morphology not only in the developing but also the adult nervous system. BMP-5 may play important roles not only in myocardial differentiation but also in the formation and maintenance of endocardial cushion tissue. Additionally, a high expression level of BMP-5 has been detected in certain tumors of mesenchymal origin. |
| 存儲(chǔ)條件 | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
| 成立日期 | 2013-04-18 (14年) | 注冊(cè)資本 | 589.8595萬人民幣 |
| 員工人數(shù) | 100-500人 | 年?duì)I業(yè)額 | ¥ 1億以上 |
| 主營行業(yè) | 天然產(chǎn)物,生物化工,化學(xué)試劑,生物技術(shù)服務(wù) | 經(jīng)營模式 | 貿(mào)易,工廠,試劑,定制,服務(wù) |
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