王不留行環(huán)肽 A|TN2200|TargetMol

價(jià)格	￥745	￥1820	￥2690
包裝	1mg	5mg	10mg

最小起訂量	1mg
發(fā)貨地	上海
更新日期	2026-05-08

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產(chǎn)品詳情

中文名稱:王不留行環(huán)肽 A	英文名稱:Segetalin A
CAS:161875-97-4	品牌: TargetMol
產(chǎn)地: 美國	保存條件: Keep away from moisture,Keep away from direct sunlight Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
純度規(guī)格: 99.83%	產(chǎn)品類別: 抑制劑
貨號(hào): T008\|TN2200

Product Introduction

Bioactivity

名稱	Segetalin A
描述	Segetalin A is a cyclic peptide isolated from the seeds of Vaccaria hispanica; it belongs to the class of naturally occurring cyclic peptides of plant origin and exhibits weak cytotoxicity toward HEK293 cells.
體外活性	Total methanolic extracts of Saponaria vaccaria seed derived from several varieties, as well as various purified components obtained through successive chromatographic separations of total extracts were evaluated for their growth inhibitory activity in WiDr (colon), MDA-MB-231 (breast), NCI-417 (lung) and PC-3 (prostate) human cancer cells as well as the non-tumorigenic fibroblast BJ (CRL-2522) cell line using MTT colorimetric assay. Purified bisdesmosidic saponins segetoside H and I were further examined using microscopy and apoptosis assays. Bisdesmosidic saponins exhibited dose-dependent growth inhibitory and selective apoptosis-inducing activity. Growth inhibitory effects were particularly strong in a breast (MDA-MB-231) and a prostate (PC-3) cancer cell line. Total extracts exhibited a different preference being most active against a colon cancer cell line (WiDr). In a comparison of varieties, all of the total seed extracts exhibited similar dose-dependent activities, but with some variation in potency. Monodesmosidic saponins vaccarosides A and B, phenolic vaccarin, and cyclopeptide Segetalin A, co-occurring seed substituents, did not exhibit activity. The non-tumorigenic fibroblast cell line BJ (CRL 2522) was growth inhibited but did not undergo apoptosis when treated with bisdesmosidic saponins at low micromolar concentrations.
存儲(chǔ)條件	Keep away from moisture,Keep away from direct sunlight Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
溶解度	Methanol : < 1?mg/mL?(insoluble), Sonication and heating are recommended.
關(guān)鍵字	Segetalin A \| progestogenReceptor \| progestogen Receptor \| EstrogenReceptor \| Estrogen/progestogen Receptor \| Estrogen Receptor/ERR \| Estrogen Receptor
相關(guān)庫	中藥單體化合物庫 \| 中國藥典收錄天然產(chǎn)物庫 \| 高通量篩選天然產(chǎn)物庫

關(guān)鍵字：王不留行環(huán)肽 A;Vaccarin D;TargetMol

公司簡介

成立日期	2013-04-18 （14年）	注冊(cè)資本	589.8595萬人民幣
員工人數(shù)	100-500人	年?duì)I業(yè)額	￥ 1億以上
主營行業(yè)	天然產(chǎn)物,生物化工,化學(xué)試劑,生物技術(shù)服務(wù)	經(jīng)營模式	貿(mào)易,工廠,試劑,定制,服務(wù)

TargetMol 中國（陶術(shù)生物）

VIP 1年

公司成立：14年
注冊(cè)資本：589.8595萬人民幣
企業(yè)類型：股份有限公司(非上市、自然人投資或控股)
主營產(chǎn)品：活性分子、生化試劑、天然產(chǎn)物、重組蛋白、抗體相關(guān)、試劑盒、藥物篩選化合物庫、技術(shù)服務(wù)
公司地址：靜安區(qū)江場三路238號(hào)8樓

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王不留行環(huán)肽 A|TN2200|TargetMol相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱	價(jià)格		公司名稱	報(bào)價(jià)日期
王不留行環(huán)肽A，161875-97-4，科研實(shí)驗(yàn)用	詢價(jià)	VIP3年	湖北萃園生物科技有限公司	2026-06-16
王不留行環(huán)肽A	詢價(jià)		成都曼思特生物科技有限公司	2026-06-03
王不留行環(huán)肽A/161875-97-4/Segetalin A	詢價(jià)		上海鴻肽生物科技有限公司	2025-06-17
王不留行環(huán)肽A	￥2000		成都格普特生物科技有限公司	2024-06-07

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