巰基硅膠除鈀吸附劑是以高比表面積多孔硅膠為載體，通過穩(wěn)定化學(xué)鍵合技術(shù)接枝高密度巰基（-SH）官能團的功能化吸附材料。依托巰基與鈀離子（Pd2?、Pd?）的強配位絡(luò)合作用，可快速、高選擇性地深度捕集體系中各類形態(tài)鈀雜質(zhì)，包括游離鈀離子、膠體鈀、鈀碳微粒及鈀 - 膦絡(luò)合物。產(chǎn)品機械強度高、耐酸堿、不溶脹、無官能團溶出，兼容甲醇、乙醇、四氫呋喃等常用制藥溶劑，適配常溫常壓操作?？蓪⒃纤?、中間體中鈀殘留從數(shù)百 ppm 穩(wěn)定降至 1ppm 以下，滿足藥典嚴(yán)苛標(biāo)準(zhǔn)，廣泛用于 Suzuki、Heck 等鈀催化反應(yīng)后處理，兼具貴金屬回收價值，符合 GMP 規(guī)范。

Thiol-Functionalized Silica Gel for Palladium ScavengingThiol-functionalized silica gel is a high-performance adsorbent material, which is prepared by chemically bonding high-density thiol (-SH) groups onto the surface of porous silica gel with large specific surface area. Relying on the strong coordination and complexation between thiol groups and palladium species (Pd2?, Pd?), it can rapidly and highly selectively capture various forms of palladium impurities in the system, including free palladium ions, colloidal palladium, palladium on carbon particles, and palladium-phosphine complexes. This product features high mechanical strength, acid and alkali resistance, non-swelling property, and no functional group leaching. It is compatible with common pharmaceutical solvents such as methanol, ethanol, and tetrahydrofuran, and can operate under ambient temperature and pressure. It can stably reduce palladium residues in APIs and intermediates from hundreds of ppm to below 1 ppm, meeting strict pharmacopoeia standards. Widely used in post-treatment of palladium-catalyzed reactions such as Suzuki and Heck couplings, it also has the value of precious metal recovery and complies with GMP regulations。