PKC nu, Human, 重組蛋白 (GST),PKC nu Protein, Human, Recombinant (GST)

PKC nu, Human, 重組蛋白 (GST)|TMPY-04456|TargetMol

價(jià)格	￥2530
包裝	50μg

最小起訂量	50μg
發(fā)貨地	上海
更新日期	2026-05-11

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產(chǎn)品詳情

中文名稱:PKC nu, Human, 重組蛋白 (GST)	英文名稱:PKC nu Protein, Human, Recombinant (GST)
品牌: TargetMol	產(chǎn)地: 美國(guó)
保存條件: Store at low temperature Store at -80°C	產(chǎn)品類別: 抑制劑
種屬: Human	表達(dá)系統(tǒng): Baculovirus Insect Cells
蛋白長(zhǎng)度: A DNA sequence encoding the full length of human PRKD3 (NP_005804.1) (Met 1-Pro 890) was expressed with the GST tag at the N-terminus. Predicted N terminal: Met	標(biāo)簽: N-GST
貨號(hào): T011\|TMPY-04456

Product Introduction

Bioactivity

名稱	PKC nu Protein, Human, Recombinant (GST)
描述	Serine/threonine-protein kinase D3, also known as Protein kinase C nu type, Protein kinase EPK2, PRKD3, EPK2 and PRKCN, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD3 / PRKCN contains one PH domain, two phorbol-ester/DAG-type zinc fingers and one protein kinase domain. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. They also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. PRKD3 / PRKCN converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. It is involved in resistance to oxidative stress. PRKD3 / PRKCN is activated by DAG and phorbol esters. Phorbol-ester/DAG-type domains 1 and 2 bind both DAG and phorbol ester with high affinity and mediate translocation to the cell membrane. Autophosphorylation of Ser-735 and phosphorylation of Ser-731 by PKC relieves auto-inhibition by the PH domain. PRKD3 / PRKCN can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. PRKD3 / PRKCN can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phospholipase C gamma and the involvement of other PKC family members.
存儲(chǔ)條件	Store at low temperature Store at -80°C
關(guān)鍵字	PKD-3 \| PKD 3 \| EPK-2 \| EPK 2

關(guān)鍵字： protein kinase D3;PRKCN;PKD3;PKC-NU;nPKC-NU;EPK2;TargetMol

公司簡(jiǎn)介

成立日期	2013-04-18 （14年）	注冊(cè)資本	589.8595萬人民幣
員工人數(shù)	100-500人	年?duì)I業(yè)額	￥ 1億以上
主營(yíng)行業(yè)	天然產(chǎn)物,生物化工,化學(xué)試劑,生物技術(shù)服務(wù)	經(jīng)營(yíng)模式	貿(mào)易,工廠,試劑,定制,服務(wù)

TargetMol 中國(guó)（陶術(shù)生物）

VIP 1年

公司成立：14年
注冊(cè)資本：589.8595萬人民幣
企業(yè)類型：股份有限公司(非上市、自然人投資或控股)
主營(yíng)產(chǎn)品：活性分子、生化試劑、天然產(chǎn)物、重組蛋白、抗體相關(guān)、試劑盒、藥物篩選化合物庫、技術(shù)服務(wù)
公司地址：靜安區(qū)江場(chǎng)三路238號(hào)8樓

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