SDF-1 alpha/CXCL12, Mouse, 重組蛋白

價格	￥17300
包裝	1mg

最小起訂量	1mg
發(fā)貨地	上海
更新日期	2026-05-15

QQ交談微信洽談

產(chǎn)品詳情

中文名稱:SDF-1 alpha/CXCL12, Mouse, 重組蛋白	英文名稱:SDF-1 alpha/CXCL12 Protein, Mouse, Recombinant
品牌: TargetMol	產(chǎn)地: 美國
保存條件: Store at low temperature Lyophilized powder: -20~-80°C for 1 year \| Solution: -80°C for 6 months	純度規(guī)格: 98.00%
產(chǎn)品類別: 抑制劑
種屬: Mouse	表達系統(tǒng): E. coli
蛋白長度: Lys22-Lys89	標簽: Tag Free
貨號: T011\|TMPJ-00952

Product Introduction

Bioactivity

名稱	SDF-1 alpha/CXCL12 Protein, Mouse, Recombinant
描述	Mouse Cxcl12 is a secreted and highly conserved protein which belongs to the intercrine alpha (chemokine CxC) family.CXCL12 is widely expressed in various organs including brain, kidney, skeletal muscle, heart, liver, and lymphoid organs. Cxcl12 activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. It also binds to atypical chemokine receptor ACKR3 which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1. Cxcl12 has several critical functions during embryonic development such as B-cell lymphopoiesis, myelopoiesis in bone marrow and heart ventricular septum formation. Cxcl12 plays an important role in acting as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. It stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and ACKR3, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through LYN kinase. It also plays a protective role after myocardial infarction, induces down-regulation and internalization of ACKR3 expressed in various cells and stimulates the proliferation of bone marrow-derived b progenitor cells in the presence of IL-7 as well as growth of the stromal cell-dependent B-cell clone DW34 cells.
存儲條件	Store at low temperature Lyophilized powder: -20~-80°C for 1 year \| Solution: -80°C for 6 months
關(guān)鍵字	TPAR-1 \| TPAR 1 \| SDF1 \| SDF 1

關(guān)鍵字： TPAR1;TLSF;Thymic lymphoma cell-stimulating factor;Stromal cell-derived factor 1;SDF-1;Sdf1;Pre-B cell growth-stimulating factor;PBSF;Cxcl12;C-X-C motif chemokine 12;12-O-tetradecanoylphorbol 13-acetate repressed protein 1;TargetMol

公司簡介

TargetMol Chemicals Inc. 總部位于馬薩諸塞州波士頓，致力于為全球生化領(lǐng)域科學家的研究提供專業(yè)的產(chǎn)品和服務(wù)。TargetMol?品牌的客戶群分布于40多個國家和地區(qū)，已發(fā)展成為全球知名的化合物庫和小分子化合物研究供應商。 TargetMol?可提供160多種滿足不同需求的化合物庫，以及多種類型的生化試劑產(chǎn)品，包括12000多種抑制劑、16000多種天然產(chǎn)物和各類多肽、抗體、生命科學試劑盒等，此外，我們還建設(shè)有CADD（計算機輔助藥物設(shè)計）研究中心、藥理實驗室、藥化合成平臺三大技術(shù)中心，全方位滿足客戶的定制需求。憑借我們優(yōu)質(zhì)的產(chǎn)品和服務(wù)、快速高效的全球供應鏈和專業(yè)的技術(shù)支持，我們將有效幫助您縮短研發(fā)周期，取得更成功的結(jié)果。

成立日期	2013-04-18 （14年）	注冊資本	589.8595萬人民幣
員工人數(shù)	100-500人	年營業(yè)額	￥ 1億以上
主營行業(yè)	中間體,天然產(chǎn)物,生物化工,化學試劑,生物技術(shù)服務(wù)	經(jīng)營模式	貿(mào)易,工廠,試劑,定制,服務(wù)

TargetMol中國（陶術(shù)生物）

VIP 3年

公司成立：14年
注冊資本：589.8595萬人民幣
企業(yè)類型：有限責任公司(自然人投資或控股)
主營產(chǎn)品：抑制劑&激動劑，天然產(chǎn)物，重組蛋白，化合物庫，技術(shù)服務(wù)
公司地址：上海市靜安區(qū)江場三路238號8樓

進入店鋪

詢盤

店內(nèi)推薦

IgG1 hFc, Human, 重組蛋白, Biotinylated

￥6130

Galectin-3/LGALS3, Mouse, 重組蛋白 (His)

￥10600

SHP-1/PTPN6, Human, 重組蛋白 (His)

￥17300