| 中文名稱:化合物 Streptolydigin | 英文名稱:Streptolydigin |
| CAS:7229-50-7 | 品牌: TargetMol |
| 產(chǎn)地: 美國(guó) | 保存條件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 產(chǎn)品類別: 抑制劑 | |
| 貨號(hào): T001|T16945 |
| 名稱 | Streptolydigin |
| 描述 | Streptolydigin inhibits RNA synthesis by binding to RNA polymerase and does not inhibit eukaryotic RNA polymerases. Streptolydigin is a 3-acetyltetramic acid antibiotic and a potent bacterial RNA polymerase inhibitor (Ki: 18 μM and a Kd: 15 μM). |
| 體外活性 | Streptolydigin inhibits initiation, elongation, and pyrophosphorolysis by bacterial RNA polymerase. Streptolydigin inhibits T. thermophilus RNA polymerase (a Ki: 1.8 μM). Binding of Streptolydigin to RNA polymerase strictly depends on a noncatalytic magnesium ion which is likely chelated by the aspartate of the bridge helix of the active center. Streptolydigin interacts with three structural elements within RNAP: the Stl pocket, the bridge helix, and the trigger-loop region. The Streptolydigin streptolol moiety interacts with the Streptolydigin pocket and bridge helix, and the Streptolydigin tetramic-acid moiety interacts with the trigger-loop region [1][3]. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 關(guān)鍵字 | Streptolydigin | Bacterial RNA polymerase |
| 相關(guān)產(chǎn)品 | Adipic dihydrazide | Levulinic acid | Doxycycline | Neomycin sulfate | Terbinafine hydrochloride | BES | Sodium bicarbonate | Hyaluronic acid sodium (MW 20 kDa) | Sodium diacetate | Sulfamethoxazole sodium | Kanamycin sulfate | D(+)-Raffinose pentahydrate |
| 成立日期 | 2013-04-18 (14年) | 注冊(cè)資本 | 589.8595萬(wàn)人民幣 |
| 員工人數(shù) | 100-500人 | 年?duì)I業(yè)額 | ¥ 1億以上 |
| 主營(yíng)行業(yè) | 中間體,天然產(chǎn)物,生物化工,化學(xué)試劑,生物技術(shù)服務(wù) | 經(jīng)營(yíng)模式 | 貿(mào)易,工廠,試劑,定制,服務(wù) |
| 產(chǎn)品名稱 | 價(jià)格 | 公司名稱 | 報(bào)價(jià)日期 | |
|---|---|---|---|---|
| 詢價(jià) |
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2026-07-22 | ||
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VIP1年
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2026-06-10 | |
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VIP1年
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河南伊諾凱新材料有限公司
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2026-06-11 |