Product Name：Periplanetasin-4
CAS No.： 2206807-06-7
Synonyms：美洲蟑螂抗菌肽Periplanetasin-4
Catalog No.：220P384
Brand：Typeptide Biotech（肽研生物）
Description：Periplanetasin-4是一種可從美洲蟑螂 (Periplaneta americana) 中提取的抗菌肽，是由13個(gè)氨基酸組成的多肽。Periplanetasin-4 減少細(xì)胞圓化和凋亡 (apoptosis)。Periplanetasin-4 阻斷 Clostridium difficile toxin A 誘導(dǎo)的 ROS 產(chǎn)生以及下游 p38 MAPK 和 p21 的激活。Periplanetasin-4顯著增加Candida albicans ATCC 90028細(xì)胞中的線粒體鈣水平，降低 DPH 熒光強(qiáng)度，并引發(fā)液泡功能障礙。Periplanetasin-4 顯著改善小鼠腸道中毒素 A 誘導(dǎo)的黏膜損傷。Periplanetasin-4 可用于結(jié)腸炎的研究。
Periplanetasin-4 is an antimicrobial peptide extracted from American cockroaches (Periplaneta Americana), consisting of 13 amino acids. Periplanetasin-4 reduces cell rounding and apoptosis. Periplanetasin-4 blocks ROS production induced by Clostridium difficile toxin A and downstream activation of p38 MAPK and p21. Periplanetasin-4 significantly increases mitochondrial calcium levels in Candida albicans ATCC 90028 cells, reduces DPH fluorescence intensity, and induces vacuolar dysfunction. Periplanetasin-4 significantly improved mucosal damage induced by enterotoxin A in mice. Periplanetasin-4 can be used for research on colitis.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | LRHKVYGYCVLGP-NH2 |
Sequence(3-letter code) | H-Leu-Arg-His-Lys-Val-Tyr-Gly-Tyr-Cys-Val-Leu-Gly-Pro-NH2 |
Peptide Structure | 
|
Molecular Formula | C70H110N20O15S1 |
Molecular Weight | 1503.81 |
訂購(gòu)聯(lián)系方式：
南京肽研生物生物科技有限公司
手機(jī)號(hào)：19961912513(微信同號(hào))
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用，不得用于人體。
關(guān)鍵字： Periplanetasin-4;美洲蟑螂抗菌肽Periplanetasi;2206807-06-7;多肽;多肽合成;
肽研生物坐落于國(guó)家級(jí)新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷(xiāo)售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠(chéng)信、嚴(yán) 謹(jǐn)、務(wù)實(shí)”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類(lèi)型和優(yōu)質(zhì)的產(chǎn)品。