Name: hydroxypropyl- beta-cyclodextrin
Other name : hydroxypropyl betadex ; 2-hydroxypropyl-beta-cyclodextirn ;
Hydroxypropyl-β-cyclodextrin .
Abbreviation : HPBCD
CAS: 128446-35-5; 94035-02-6; 136019-12-0
EINECS: 420-920-1
Molecular formula : C42H70-nO35(C3H8O2)n
Molecular weight: 1134.98+58n
Solubility(in 100cm3 solvent, at 25℃) : water: >180 g
Methanol: >33g
DMSO: >33g
Qaulity ： Pharma grade / food grade / cosmetics grade / industry grade
Standard : USP40-NF35/ EP9.0 / CP2015
Package: 500g/bag , 2kg/bag, 10kg/drum , 20kg/drum
Use : medical \ food \ chemical \ cosmetic \ other industries
Specification :
white powder, insipid, innocent
50%(w/v) water solution is clear
same absorption bands with USP Hydroxypropyl Betadex RS
10%(w/v) water solution ≤200µS/cm
Salmonella/E. Coli (cfu/g)
Storage: at room temperature, in tightly closed container.
Applications:
Hydroxypropyl-β-cyclodextrin (HP-β-CD) is one of the most widely used cyclodextrin derivatives in current scientific researches and industry applications. It mainly used in food, pharmaceutical and cosmetics industries.
1. In pharmaceuticals industry, HP-β-CD can increase solubility and bioavailability of insoluble drugs, so that the efficacy of drugs can last longer with less ingestion of drugs. It can adjust and control drugs release ratio, decrease side effects of drugs, and enhance stability of drugs. HP-β-CD can be used for oral medication, injection, mucosal delivery systems (including the nasal mucosa, rectum, cornea, etc.), dermal drug delivery systems, lipophilic drugs targeting delivery, and also used as protective agent and stabilizer of protein.
2. In food and perfume industry, HP-β-CD can enhance the stability of nutritional constituent and extend active time of effective constituent. It can cover up bad smell and bad taste of nutritional constituent. It also can improve production processes and product quality.
3. In cosmetics industry, HP-β-CD can reduce stimulate of organic molecular in cosmetic to the skin and mucosa. It can enhance the stability of matter, by preventing oxidation and volatilization of nutrients.
關(guān)鍵字： 羥丙基倍他環(huán)糊精;羥丙基-beta-環(huán)糊精;羥丙基-β-環(huán)糊精;2-羥丙基倍他環(huán)糊精
智源生物是一家專注于環(huán)糊精衍生物、環(huán)糊精包合物、殼聚糖衍生物的研發(fā)、生產(chǎn)、應(yīng)用于一體的高新技術(shù)企業(yè)，擁有年綜合生產(chǎn)能力1萬(wàn)噸的現(xiàn)代化生產(chǎn)基地，具備完善的管理體系和專業(yè)的科研團(tuán)隊(duì)。
智源生物擁有環(huán)糊精衍生物、環(huán)糊精包合物、殼聚糖衍生物、環(huán)糊精試劑、化妝品原料、包合定制六大類70多個(gè)品種，產(chǎn)品廣泛應(yīng)用于藥用輔料、化妝品配料、功能食品、香精香料等領(lǐng)域，是國(guó)內(nèi)環(huán)糊精種類豐富、規(guī)格齊全的生產(chǎn)型企業(yè)。
智源生物已通過(guò)ISO9001:2015質(zhì)量管理、ISO14001:2015環(huán)境管理，ISO45001:2018職業(yè)健康安全三大體系認(rèn)證及猶太、清真認(rèn)證。公司擁有2000m2高標(biāo)準(zhǔn)GMP車間，配備50余臺(tái)國(guó)際先進(jìn)檢測(cè)設(shè)備，實(shí)現(xiàn)從原料到成品的全程自主檢測(cè)，確保產(chǎn)品質(zhì)量穩(wěn)定可靠。
智源生物在濟(jì)南建有研發(fā)中心，攜手山東大學(xué)、南開(kāi)大學(xué)、中國(guó)藥科大學(xué)、復(fù)旦大學(xué)共建環(huán)糊精應(yīng)用研究中心、環(huán)糊精協(xié)同創(chuàng)新中心、共建環(huán)糊精實(shí)驗(yàn)室等創(chuàng)新平臺(tái)。公司以國(guó)際一流標(biāo)準(zhǔn)建成應(yīng)用研發(fā)中心等5處省市級(jí)研發(fā)平臺(tái)，先后承擔(dān)科技部“科技助力經(jīng)濟(jì)2020"等多項(xiàng)國(guó)家級(jí)、省級(jí)重大科研項(xiàng)目。
核心產(chǎn)品已通過(guò)全球權(quán)威認(rèn)證羥丙基倍他環(huán)糊精、碘丁基倍他環(huán)糊精鈉、羥丙基伽馬環(huán)糊精、甲基倍他環(huán)糊精、羥丙基殼聚糖均成功完成CDE備案登記。其中羥丙基倍他環(huán)糊精、碘丁基倍他環(huán)糊精鈉、羥丙基伽馬環(huán)糊精順利通過(guò)FDA登記備案，羥丙基倍他環(huán)糊精、磺丁基倍他環(huán)糊精鈉已獲得EDQN-CEP證書?；瘖y品新原料-超支化環(huán)糊精成功取得國(guó)妝原備字20250095備案。
智源生物是國(guó)家級(jí)高新技術(shù)企業(yè)十四五國(guó)家重點(diǎn)支持的國(guó)家級(jí)專精特新重點(diǎn)“小巨人”企業(yè)，山東省瞪羚企業(yè)，山東省中小企業(yè)"隱形冠軍"，濱州市新興產(chǎn)業(yè)白名單企業(yè)，濱州市守合同重信用企業(yè)。智源生物產(chǎn)品均擁有自主知識(shí)產(chǎn)權(quán)，憑借卓越品質(zhì)與技術(shù)實(shí)力，通過(guò)輝瑞、強(qiáng)生、吉利德科學(xué)、先聲藥業(yè)、麗珠制藥集團(tuán)等國(guó)內(nèi)外藥企審計(jì)。產(chǎn)品遠(yuǎn)銷歐美、日韓、印巴、南美、中東等多個(gè)國(guó)家和地區(qū)，贏得高度認(rèn)可和贊譽(yù)!我們的使命：探求環(huán)糊精在人類活動(dòng)中的無(wú)限應(yīng)用。 我們的愿景：做全球環(huán)糊精領(lǐng)域領(lǐng)軍者。 我們始終以客戶為本，以優(yōu)質(zhì)的產(chǎn)品和服務(wù)回饋客戶！ 我們期待與您合作，共同推動(dòng)環(huán)糊精科學(xué)的美好未來(lái)。