• 中文名稱：

• 維羅非尼

• 英文名稱：

• vemurafenib

• 英文別名：

• Vemurafenib (PLX4032,RG7204)

• CAS號：

• 918504-65-1

• 分子式：

• C23H18ClF2N3O3S

• 分子量：

• 489.92200

• 精確質(zhì)量：

• 489.07300

• PSA：

• 100.30000

• LogP：

• 6.69800

Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600