| 價(jià)格 | 詢價(jià) |
| 包裝 | 10μg |
| 最小起訂量 | 10μg |
| 發(fā)貨地 | 上海 |
| 更新日期 | 2026-06-09 |
| 中文名稱:Recombinant Human IL-36β, 157a.a. | 英文名稱:Recombinant Human IL-36β, 157a.a. |
| 有效期: 一年 | 產(chǎn)品類(lèi)別: 重組蛋白 細(xì)胞因子 |
| 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | 產(chǎn)品包裝 | 產(chǎn)品價(jià)格 |
| P5255-10μg | Recombinant Human IL-36β, 157a.a. | 10μg | 詢價(jià) |
| Species | Gene ID | Accession | Source | Length | MW | Tag |
| Human | 27177 | Q9NZH7 | E. coli | 157aa | 17.7kDa | - |
| About this protein | |
| Name | Recombinant Human IL-36β, 157a.a. (Recombinant Human Interleukin-36β, 157a.a.; rHuIL-36β, 157a.a.);重組人白細(xì)胞介素36β,157a.a. |
| Synonyms | IL36B; IL1F8; IL1H2 |
| Purity | >97% by SDS-PAGE and HPLC analyses. |
| Biological Activity | Fully biologically active when compared to standard. The specific activity is determined by its binding ability in a functional ELISA. Immobilized rHuIL-36β at 1μg/ml can bind recombinant human IL-1 Rrp2 Fc Chimera with a range of 0.15-5μg/ml. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4. |
| Endotoxin | Less than 1EU/μg of rHuIL-36β, 157a.a. as determined by LAL method. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
| Category | Cytokine |
| Background | Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in the pathophysiology of several diseases. IL-36α, IL-36β, and IL-36γ (formerly IL-1F6, IL-1F8, and IL-1F9) are IL-1 family members that signal through the IL-1 receptor family members IL-1Rrp2 (IL-1RL2) and IL-1RAcP. IL-36 beta is reported to be expressed at higher levels in psoriatic plaques than in symptomless psoriatic skin or healthy control skin. Furthermore, it can stimulate production of interleukin-6 and interleukin-8 in synovial fibroblasts, articular chondrocytes and mature adipocytes. Two alternatively spliced transcript variants encode distinct (164 or 157 residues) protein isoforms that differ in their C-terminal 70 amino acid residues have been reported and IL-36β isoform 2 is synthesized as a 157a.a. protein. Specifically, human IL-36β shares low sequence identity with IL-1β, IL-36RA, IL-36α and IL-36γ. |
| Amino Acid Sequence | MNPQREAAPK SYAIRDSRQM VWVLSGNSLI AAPLSRSIKP VTLHLIACRD TEFSDKEKGN MVYLGIKGKD LCLFCAEIQG KPTLQLKEKN IMDLYVEKKA QKPFLFFHNK EGSTSVFQSV SYPGWFIATS TTSGQPIFLT KERGITNNTN FYLDSVE |
包裝清單:
| 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | 包裝 |
| P5255-2μg | Recombinant Human IL-36β, 157a.a. | 2μg |
| P5255-10μg | Recombinant Human IL-36β, 157a.a. | 10μg |
| P5255-100μg | Recombinant Human IL-36β, 157a.a. | 100μg |
| P5255-1mg | Recombinant Human IL-36β, 157a.a. | 1mg |
| - | 說(shuō)明書(shū) | 1份 |
保存條件:
???????-20℃或更低溫度保存,至少一年有效。由于蛋白的每次凍融均會(huì)引起部分失活,所以首次配制成相應(yīng)濃度的儲(chǔ)存液后(請(qǐng)根據(jù)產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液),須分裝后-20℃或更低溫度凍存,以避免反復(fù)凍融。
注意事項(xiàng):
???????由于有些塑料管壁對(duì)某些蛋白有較強(qiáng)的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein,如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)合位點(diǎn),使細(xì)胞因子或重組蛋白不會(huì)粘附于管壁。所以一定要使用產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液。
???????本產(chǎn)品僅限于專(zhuān)業(yè)人員的科學(xué)研究用,不得用于臨床診斷或治療,不得用于食品或藥品,不得存放于普通住宅內(nèi)。
???????為了您的安全和健康,請(qǐng)穿實(shí)驗(yàn)服并戴一次性手套操作。
| 成立日期 | 2007-07-19 (19年) | 注冊(cè)資本 | 1000.000000萬(wàn)人民幣 |
| 員工人數(shù) | 500人以上 | 年?duì)I業(yè)額 | ¥ 500萬(wàn)-1000萬(wàn) |
| 主營(yíng)行業(yè) | 生化試劑,核苷,核苷酸,寡核苷酸,抗體,蛋白組學(xué),生物活性小分子 | 經(jīng)營(yíng)模式 | 試劑 |
| 產(chǎn)品名稱 | 價(jià)格 | 公司名稱 | 報(bào)價(jià)日期 | |
|---|---|---|---|---|
| ¥646 |
VIP7年
|
上??道噬锟萍加邢薰?/div>
|
2026-06-17 | |
| ¥1950 |
VIP4年
|
上海滬震實(shí)業(yè)有限公司
|
2026-06-17 | |
| ¥3300 |
VIP1年
|
上海撫生實(shí)業(yè)有限公司
|
2026-06-17 | |
| ¥3300 |
VIP1年
|
上海西格生物科技有限公司
|
2026-06-17 |