| 價格 | 詢價 |
| 包裝 | 100μg |
| 最小起訂量 | 100μg |
| 發(fā)貨地 | 上海 |
| 更新日期 | 2026-07-12 |
| 中文名稱:Recombinant Human IL-1 RA | 英文名稱:Recombinant Human IL-1 RA |
| 有效期: 一年 | 產(chǎn)品類別: 重組蛋白 細(xì)胞因子 |
| 產(chǎn)品編號 | 產(chǎn)品名稱 | 產(chǎn)品包裝 | 產(chǎn)品價格 |
| P5111-100μg | Recombinant Human IL-1 RA | 100μg | 詢價 |
| Species | Gene ID | Accession | Source | Length | MW | Tag |
| Human | 3557 | P18510 | E. coli | 152aa | 17.1kDa | - |
| About this Protein | |
| Name | Recombinant Human IL-1 RA (Recombinant Human Interleukin-1 Receptor Antagonist; rHuIL-1RA);重組人白細(xì)胞介素1受體拮抗劑 |
| Synonyms | IL-1F3; IL1RN; DIRA; ICIL-1RA; IL1F3; IL1RA; IL-1ra; IL-1ra3; IL1RN; IL-1RN; Interleukin 1 receptor antagonist; IRAP; MVCD4 |
| Purity | >96% by SDS-PAGE and HPLC analyses |
| Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by inhibiting IL-1α-dependent proliferation of murine D10S cells is less than 40ng/ml, corresponding to a specific activity of >2.5×104IU/mg in the presence of 50pg/ml rHuIL-1α. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4. |
| Endotoxin | Less than 1EU/μg of rHuIL-1RA as determined by LAL method. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
| Category | Cytokine |
| Background | Interleukin-1 receptor antagonist (IL-1RA) is a member of the IL-1 family. IL-1RA is secreted by various types of cells including immune cells, epithelial cells, and adipocytes, and is a natural inhibitor of the pro-inflammatory effect of IL-1β. This protein inhibits the activities of interleukin 1, alpha (IL-1α) and interleukin 1, beta (IL-1β), and modulates a variety of interleukin 1 related immune and inflammatory responses. IL-4 and IL-13 have been shown to amplify the stimulatory effect of IL1-beta on the production of soluble and intracellular forms of IL1-RA. The regulated expression of IL-1RA in various cell types has been shown to be influenced by cytokines. In synovial fibroblasts the synthesis of IL-1RA is markedly enhanced by IL-1, TNF-α, or PDGF. The protein shows 26% amino acid homology to IL-1β and 19% homology to IL-1α. |
| Amino Acid Sequence | RPSGRKSSKM QAFRIWDVNQ KTFYLRNNQL VAGYLQGPNV NLEEKIDVVP IEPHALFLGI HGGKMCLSCV KSGDETRLQL EAVNITDLSE NRKQDKRFAF IRSDSGPTTS FESAACPGWF LCTAMEADQP VSLTNMPDEG VMVTKFYFQE DE |
包裝清單:
| 產(chǎn)品編號 | 產(chǎn)品名稱 | 包裝 |
| P5111-20μg | Recombinant Human IL-1 RA | 20μg |
| P5111-100μg | Recombinant Human IL-1 RA | 100μg |
| P5111-1mg | Recombinant Human IL-1 RA | 1mg |
| - | 說明書 | 1份 |
保存條件:
???????-20℃或更低溫度保存,至少一年有效。由于蛋白的每次凍融均會引起部分失活,所以首次配制成相應(yīng)濃度的儲存液后(請根據(jù)產(chǎn)品簡介中Reconstitution一欄的信息配制儲存液),須分裝后-20℃或更低溫度凍存,以避免反復(fù)凍融。
注意事項:
???????由于有些塑料管壁對某些蛋白有較強(qiáng)的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein,如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)合位點(diǎn),使細(xì)胞因子或重組蛋白不會粘附于管壁。所以一定要使用產(chǎn)品簡介中Reconstitution一欄的信息配制儲存液。
???????本產(chǎn)品僅限于專業(yè)人員的科學(xué)研究用,不得用于臨床診斷或治療,不得用于食品或藥品,不得存放于普通住宅內(nèi)。
???????為了您的安全和健康,請穿實驗服并戴一次性手套操作。
| 成立日期 | 2007-07-19 (20年) | 注冊資本 | 1000.000000萬人民幣 |
| 員工人數(shù) | 500人以上 | 年營業(yè)額 | ¥ 500萬-1000萬 |
| 主營行業(yè) | 生化試劑,核苷,核苷酸,寡核苷酸,抗體,蛋白組學(xué),生物活性小分子 | 經(jīng)營模式 | 試劑 |
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|---|---|---|---|---|
| ¥646 |
VIP7年
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2026-07-27 | |
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