Recombinant Human alpha-2-HS-Glycoprotein is produced by our Mammalian expression system and the target gene encoding Ala19-Val367 is expressed with a 6His tag at the C-terminus.
Background
α-2-HS Glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. In addition, AHSG may influence the resolution of inflammation by modulating the phagocytosis of apoptotic cells by macrophages. ASHG blocks TGF-beta-dependent signaling in osteoblastic cells.
Storage
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
Reconstitution
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
關(guān)鍵字： Recombinant Human Fetuin A/AHSG;細(xì)胞生物學(xué)
北京索萊寶科技有限公司是一家集研發(fā)、生產(chǎn)、銷售、服務(wù)于一體的高科技生物企業(yè)。技術(shù)推廣;技術(shù)轉(zhuǎn)讓；技術(shù)咨詢；技術(shù)服務(wù)；生物試劑技術(shù)開(kāi)發(fā)；銷售生物試劑盒、實(shí)驗(yàn)室專用化學(xué)試劑、實(shí)驗(yàn)室專用設(shè)備、辦公用品、化工產(chǎn)品（不含危險(xiǎn)化學(xué)品）、計(jì)算機(jī)軟件及輔助設(shè)備；貨物進(jìn)出口、技術(shù)進(jìn)出口、代理進(jìn)出口；委托加工生產(chǎn)生物制品、生化制品、化工產(chǎn)品（不含危險(xiǎn)化學(xué)品）；生產(chǎn)生物試劑盒；批發(fā)第一類醫(yī)療器械、第二類醫(yī)療器械；批發(fā)第三類醫(yī)療器械。