Anti-CD163 antibody

Cat. No. ?? ?JC260965?
Package?? ?25 μl/100 μl/200 μl
Storage?? ?-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description ? ? ? ? ? ? ? ?? ?Anti-CD163 rabbit polyclonal antibody
Applications ? ??? ?ELISA, IHC?
Immunogen ? ? ? ? ? ?? ?Synthetic peptide of human CD163
Reactivity ? ? ? ? ? ? ?? ?Human
Content ? ? ? ? ? ? ? ? ?? ?0.2 mg/ml
Host species ? ? ? ? ? ?? ?Rabbit
Ig class ? ? ? ? ? ? ??? ?Immunogen-specific rabbit IgG
Purification ? ? ? ? ? ? ?? ?Antigen affinity purification

Target information
Symbol ? ? ? ? ? ? ?? ?CD163
Full name ? ? ? ? ? ? ?? ?CD163 molecule
Synonyms?? ?M130; MM130
Swissprot?? ?Q86VB7

Target Background
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Anti-CD163 antibody
Applications
Immunohistochemistry
Predicted cell location: secreted
Positive control: Human gasrtic cancer
Recommended dilution: 25-100?? ?Predicted cell location: secreted
Positive control: Human thyroid cancer
Recommended dilution: 25-100