柳氮磺吡啶基本信息MSDS用途與合成方法柳氮磺吡啶價格(試劑級)上下游產品信息中文名稱:柳氮磺吡啶中文同義詞:柳氮磺吡啶;柳氮磺胺吡啶-D3;5-[對-(2-吡啶胺磺酰基)苯]偶氮水楊酸;磺胺偶氮吡啶;硫氮磺吡啶;柳氮吡啶;柳氮磺胺吡啶;水楊酸偶氮磺胺吡啶英文名稱:Sulfasalazine英文同義詞:salicylazosulfapyridine;SALAZOSULFAPYRIDINE;SULFASALAZINE;SSZ;LABOTEST-BBLT00772281;5-(p-(2-pyridylsulfamoyl)phenylazo)salicylicacid;5-[4-(2-PYRIDYLSULFAMOYL)PHENYLAZO]SALICYLICACID;Benzoicacid,2-hydroxy-5-4-(2-pyridinylamino)sulfonylphenylazo-CAS號:599-79-1分子式:C18H14N4O5S分子量:398.4EINECS號:209-974-3相關類別:中間體;小分子抑制劑;原料藥;有機原料;磺胺類產品;原料;APIs;AntibioticsforResearchandExperimentalUse;Biochemistry;Cytokinesignaling;Amines;Aromatics;Heterocycles;Sulfur&SeleniumCompounds;AZULFIDINE;OtherAPIs;API;有機化工原料;Sulfonamides(AntibioticsforResearchandExperimentalUse);Intermediates&FineChemicals;PharmaceuticalsMol文件:599-79-1.mol柳氮磺吡啶性質熔點260-265°C(dec.)(lit.)沸點689.3±65.0°C(Predicted)密度1.3742(roughestimate)折射率1.6000(estimate)儲存條件Refrigerator溶解度NH4OH1M:50mg/mL,clear,red酸度系數(shù)(pKa)pKa0.6(H2Ot=20I<0.001)(Uncertain);2.4(H2Ot=20I<0.001)(Uncertain);9.7(H2Ot=20I<0.001)(Uncertain);11.8(H2Ot=20I<0.001)(Uncertain)形態(tài)powder水溶解性<0.1g/100mLat25ºCMerck14,8942BRN356241InChIKeyNCEXYHBECQHGNR-QZQOTICOSA-NCAS數(shù)據(jù)庫599-79-1(CASDataBaseReference)EPA化學物質信息Salicylazosulfapyridine(599-79-1)柳氮磺吡啶用途與合成方法化學性質其外觀為棕黃色微細結晶，無臭。微溶于乙醇，不溶于水、氯仿、乙醚、苯。用途腸道磺胺藥，與結締組織有特殊的親和力，系目前治療慢性潰瘍結膜炎較好的藥物生產方法2-氨基吡啶與N-乙酰氨基-苯磺酰氯反應，隨后水解得到磺酰吡啶胺，即磺胺吡啶，磺胺吡啶重氮化后與水楊酸偶合、酸化即制得柳氮磺胺吡啶。