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Polyquaternium-10 – is it safe?

Oct 21,2019

What is polyquaternium-10?

In our first post about conditioning ingredients, we will tell you about the benefits of polyquaternium-10 (PQ10).  PQ10 is basically cellulose that has been reacted a couple different ways.  Cellulose comes from plants, and it’s also the most abundant polymer found in nature!  How about that? 

The precursor to polyquaternium-10 is hydroxyethyl cellulose (HEC).  HEC is used in a wide variety of applications from paints, coatings, drugs, household products, and also cosmetics.  It’s a thickener and it also helps binding materials together.  In paints, it helps the paint coat the wall completely.

When HEC is quaternized to make polyquaternium-10, it has the added benefit of being attracted to damaged parts of the hair where you need it most.  Damaged hair is hard to comb, so adding PQ-10 to those parts improves combability and feel of the hair to the touch.  It’s basically a seeking missile that will destroy your bad hair day! 

Is polyquaternium-10 safe?

There isn’t a CIR report I could find to link on this product, but it’s been very heavily studied for cosmetic use for several decades.  There is a report that can be found here.  It puts the conclusions on the page but there is a full report available with all the data in a link on the page (it’s not free). 

If you want the bottom line here’s the conclusion. PQ-10 was neither an irritant nor a human sensitizer when tested at 2.0%. Cosmetic products containing up to 1% PQ-10 were not human irritants, sensitizers, or photosensitizers. On the basis of the information presented, it is concluded that PQ-10 is safe as a cosmetic ingredient in the present practices of use.

You would almost never have a good reason to use PQ-10 above 1% in a formulation.  I’ve never seen it used above that amount in all my years formulating.  It would probably make the formula a bit too sticky and unpleasant at high levels like that.  The data show it’s commpletely safe.

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Polyquaternium-10

68610-92-4

Polyquaternium-10 manufacturers

  • Polyquaternium-10
  • 68610-92-4 Polyquaternium-10
  • 2026-05-28
  • CAS:68610-92-4
  • Min. Order: 1KG
  • Purity: 99.9%
  • Supply Ability: 100000kg
  • Polyquaternium-10
  • 68610-92-4 Polyquaternium-10
  • $1.00
  • 2026-03-20
  • CAS:68610-92-4
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 mt

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