一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

ChemicalBook >> journal list >> Nutrients >>article
Nutrients

Nutrients

IF: 4.8
Download PDF

Aspartame Safety as a Food Sweetener and Related Health Hazards.

Published:18 August 2023 DOI: 10.3390/nu15163627 PMID: 37630817
Shurooq Asaad Abdulameer Shaher, Dan Florin Mihailescu, Bogdan Amuzescu

Abstract

Aspartame is the methyl-ester of the aspartate-phenylalanine dipeptide. Over time, it has become a very popular artificial sweetener. However, since its approval by the main food safety agencies, several concerns have been raised related to neuropsychiatric effects and neurotoxicity due to its ability to activate glutamate receptors, as well as carcinogenic risks due to the increased production of reactive oxygen species. Within this review, we critically evaluate reports concerning the safety of aspartame. Some studies evidenced subtle mood and behavioral changes upon daily high-dose intake below the admitted limit. Epidemiology studies also evidenced associations between daily aspartame intake and a higher predisposition for malignant diseases, like non-Hodgkin lymphomas and multiple myelomas, particularly in males, but an association by chance still could not be excluded. While the debate over the carcinogenic risk of aspartame is ongoing, it is clear that its use may pose some dangers in peculiar cases, such as patients with seizures or other neurological diseases; it should be totally forbidden for patients with phenylketonuria, and reduced doses or complete avoidance are advisable during pregnancy. It would be also highly desirable for every product containing aspartame to clearly indicate on the label the exact amount of the substance and some risk warnings.

Similar articles

IF:0

Toxicological and safety assessment of tartrazine as a synthetic food additive on health biomarkers: A review

African Journal of Biotechnology K. Amin,?Fawzia S. Al-Shehri,etc Published: 7 February 2018
IF:0

Xylene: An overview of its health hazards and preventive measures.

Journal of Oral and Maxillofacial Pathology Reena Kandyala, Sumanth Phani C Raghavendra,etc Published: 1 January 2010
IF:3.9

Erythritol as sweetener—wherefrom and whereto?

Applied Microbiology and Biotechnology K. Regnat, R. L. Mach,etc Published: 1 December 2017
江阴市| 东乡县| 余江县| 娱乐| 永昌县| 宜州市| 铁岭县| 青河县| 四子王旗| 镶黄旗| 江北区| 博湖县| 乌拉特中旗| 伊金霍洛旗| 巧家县| 阿克陶县| 宜章县| 祁东县| 高清| 郸城县| 惠安县| 台山市| 娄底市| 抚顺市| 区。| 仲巴县| 宜宾县| 垦利县| 桐柏县| 湘西| 贺州市| 松桃| 张家界市| 塔河县| 湾仔区| 三台县| 穆棱市| 和硕县| 呼伦贝尔市| 阜康市| 哈尔滨市|