一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

ChemicalBook >> journal list >> International Journal of Biological Macromolecules >>article
International Journal of Biological Macromolecules

International Journal of Biological Macromolecules

IF: 7.7
Download PDF

Enzymatic hydrolysis of duck blood protein produces stable bioactive peptides: Pilot-scale production, identification, and stability during gastrointestinal and plasma digestion

Published:1 December 2024 DOI: 10.1016/j.ijbiomac.2024.137864 PMID: 39566759
Phanthipha Laosam, Pichitpon Luasiri, Papungkorn Sangsawad

Abstract

This study addresses the valorization of duck blood, an underutilized protein-rich by-product from the poultry industry, into bioactive protein hydrolysates with antioxidant and ACE inhibitory properties. Raw and heat-treated duck blood were compared as substrates for enzymatic hydrolysis using Neutrase and Papain. Gel electrophoresis revealed that heat treatment reduced fibrinogen content, while FTIR analysis showed that heat treatment modified the protein structure, increasing β-sheet content from 21.13?% to 34.96?%. Heat-treated duck blood hydrolyzed by Neutrase exhibited superior hydrolysis (9.53?%) and protein recovery (60.28?%) compared to raw blood. Pilot-scale production (1000?L) enhanced hydrolysate yield and maintained bioactive properties. LC-MS/MS analysis identified five novel bioactive peptides derived from the hydrolysate's 4-h simulated gastrointestinal (GI) digestion, with WMHVR demonstrating the highest antioxidant and ACE inhibitory activities. Molecular docking simulations revealed that WMHVR competitively inhibits ACE by binding to the S1, S2, and S′ pockets through van der Waals and hydrogen bonding interactions. The GI-hydrolysate and identified peptides maintained bioactivity during simulated GI and blood plasma digestion, with ACE inhibition increasing over time. This research transforms food industry waste into functional protein hydrolysates, offering applications in nutraceuticals and functional foods while promoting sustainable practices through waste protein valorization.

Substances (4)

Materials
Procduct Name CAS Molecular Formula Supplier Price
Ethylenediaminetetraacetic acid 60-00-4 C10H16N2O8 1439 suppliers $6.00-$6397.62
Papain 9001-73-4 C9H14N4O3 679 suppliers $27.00-$3650.00
Ferrozine sodium 69898-45-9 C20H15N4NaO6S2 252 suppliers $10.00-$1010.00
Proteinase, Bacillus subtilis metallo- 9080-56-2 9 suppliers $56.00-$256.00

Similar articles

IF:0

Erythropoietin regulation of red blood cell production: from bench to bedside and back.

F1000Research Senthil Velan Bhoopalan,?Lily Jun-Shen Huang,etc Published: 18 September 2020
IF:5.4

Stable Gastric Pentadecapeptide BPC 157 and Wound Healing.

ACS Applied Energy Materials Sven Seiwerth, Marija Milavic,etc Published: 29 June 2021
IF:3.3

7-Azaindole Analogues as Bioactive Agents and Recent Results.

Mini reviews in medicinal chemistry Neha Sharma, Anurag,etc Published: 1 January 2019
黄梅县| 绥化市| 浦城县| 南通市| 德兴市| 昭苏县| 黎川县| 太谷县| 襄城县| 乡城县| 昆山市| 武清区| 永福县| 开阳县| 交口县| 宜良县| 民和| 甘南县| 虹口区| 毕节市| 肃宁县| 东乌| 宁安市| 丰镇市| 梅州市| 枣庄市| 沁源县| 吉木乃县| 中方县| 道孚县| 新竹县| 若羌县| 渭源县| 武川县| 松原市| 桓台县| 前郭尔| 龙门县| 克什克腾旗| 沂源县| 阳春市|