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Clobetasol propionate lotion in the treatment of moderate to severe plaque-type psoriasis.

Published:1 September 2004 DOI: PMID: 15499763
Jacques Decroix, Henrik Pres, Nicola Tsankov, Michel Poncet, Stéphanie Arsonnaud

Abstract

Owing to its anti-inflammatory, antipruritic, vasoconstrictive, and immune-modulating properties, clobetasol propionate is used to treat psoriasis. This study was conducted to evaluate the efficacy, safety, and cosmetic acceptability of clobetasol propionate lotion compared with its vehicle and with clobetasol propionate cream in the treatment of moderate to severe plaque-type psoriasis. A total of 222 patients were treated. After 4 weeks of treatment, clobetasol propionate lotion was more efficient than vehicle lotion and of equivalent efficacy as clobetasol propionate cream. Cosmetic acceptability was significantly better with clobetasol propionate lotion than with clobetasol propionate cream. Clobetasol propionate lotion was efficient, safe, and well tolerated and offers a significantly higher cosmetic advantage in the treatment of moderate to severe plaque-type psoriasis compared with clobetasol propionate cream.

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Procduct Name CAS Molecular Formula Supplier Price
Clobetasol propionate 25122-46-7 C25H32ClFO5 773 suppliers $29.00-$2000.00

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