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Journal of Dermatological Treatment

Journal of Dermatological Treatment

IF: 2.89
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Combination of benzoyl peroxide 5% gel with liquid cleanser and moisturizer SPF 30 in acne treatment results in high levels of subject satisfaction, good adherence and favorable tolerability.

Published:1 February 2018 DOI: 10.1080/09546634.2017.1342758 PMID: 28678647
Mi-Ran Kim, Nabil Kerrouche

Abstract

Background: Skin care products (cleansers and moisturizers) to complement benzoyl peroxide (BPO) in the treatment of acne may improve treatment tolerability and adherence.

Objective: Evaluate subject satisfaction after use of BPO 5% gel in combination with liquid cleanser and moisturizer SPF 30.

Methods: Open-label study including subjects aged ≥12?years with mild-to-moderate facial acne; ClinicalTrials.gov Identifier: NCT02589405. Once daily BPO 5% gel, twice daily liquid cleanser and once daily moisturizer SPF 30 were applied for 12?weeks. Assessments included a subject satisfaction questionnaire, investigator global assessment of improvement, lesion counts, the presence of Propionibacterium acnes, and safety.

Results: Fifty subjects were enrolled. Most subjects were overall satisfied with the three-part regimen (87%) and felt better about themselves (94%). Subjects indicated the skin care products helped prepare the skin for treatment (85%), relieve itchy skin (81%) and reduce irritation (87%). Most subjects considered that the liquid cleanser (80%) and moisturizer SPF 30 (84%) were a necessary part of acne treatment. BPO reduced P. acnes load by 89% at week 1. The treatment was well tolerated.

Conclusions: The combination of BPO 5% gel with liquid cleanser and moisturizer SPF 30 resulted in high levels of subject satisfaction, good tolerability and treatment adherence.

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Related products
Procduct Name CAS Molecular Formula Supplier Price
Benzoyl peroxide 94-36-0 C14H10O4 578 suppliers $23.00-$859.00
PROPIONIBACTERIUMACNES 10 suppliers Inquiry
SPF experimental animal 2 suppliers Inquiry

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