一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

ChemicalBook >> journal list >> Toxicology Mechanisms and Methods >>article
Toxicology Mechanisms and Methods

Toxicology Mechanisms and Methods

IF: 3.2
Download PDF

Syzygium Aromaticum Alleviates Cerium Chloride-Induced Neurotoxic Effect In The Adult Mice.

Published:1 January 2019 DOI: 10.1080/15376516.2018.1506849 PMID: 30064281
Yamina Kadri, Riadh Nciri, Sana Bardaa, Noura Brahmi, Saidi Saber, Abdel Halim Harrath, Waleed Aldahmash, Saleh Alwasel, Mohamed Mohany, Abdelfatteh El Feki, Mohamed Salah Allagui

Abstract

Previous studies have brought to light the toxic effect of cerium chloride (CeCl3) but very little is known about the oxidative brain injury caused by this metal. Medical plants have a well-recognized role in the management of damage caused by pollutants such as CeCl3. Syzygium aromaticum, a potent natural source of bioactive compounds and rich in secondary metabolites, has a broad range of biological functions. The aim of this study is to investigate the capacity of Syzygium aromaticum ethanol extract (ESA) to improve the adverse effects of CeCl3 in the brain tissue. Adult mice were exposed to CeCl3 (20?mg/kg body weight [BW]), with or without ESA, for 60?days. We investigate mice's behavior, damages of cholinergic system and oxidative stress parameters in mice brain. In the present study, in vitro test confirmed that ESA has antioxidant capacity attributed to the presence of flavonoids, polyphenols, and tannins contents. In vivo study showed that CeCl3 caused brain injuries manifested in memory impairment, increase in acetylcholinesterase activity, oxidative stress biomarkers (lipid, proteins, enzymatic and non-enzymatic antioxidant systems), and histopathological alteration in brain tissue. Addition of ESA repaired memory impairment, decreased acetylcholinesterase activity, restored oxidative state, and prevented histopathological alteration. In conclusion, the experimental results showed the protective effects of ethanol extract of Syzygium aromaticum against cerium-induced brain damage.

Substances (3)

Related products
Procduct Name CAS Molecular Formula Supplier Price
CERIUM(III) CHLORIDE 7790-86-5 CeCl3 370 suppliers $5.00-$1343.60
Cattail pollen extract 11 suppliers Inquiry
SYZYGIUMAROMATICUM 2 suppliers Inquiry

Similar articles

IF:3.3

Curcumin ameliorates astrocyte inflammation through AXL in cuprizone-induced mice

Toxicology and applied pharmacology Wenjing Zhang, Mengjiao Sun,etc Published: 23 November 2024
IF:1.8

Effect of the synthetic pineal peptide epitalon on spontaneous carcinogenesis in female C3H/He mice.

In vivo George Kossoy, Vladimir N Anisimov,etc Published: 1 March 2006
IF:3.7

Curcumin and Especially Tetrahydrocurcumin Ameliorate Oxidative Stress-Induced Renal Injury in Mice

Journal of Nutrition Okada Kunihiko , Wangpoengtrakul Chantima ,etc Published: 1 August 2001
黎川县| 托克托县| 贵州省| 上饶市| 宜川县| 淮安市| 澄江县| 龙南县| 从江县| 潞城市| 讷河市| 顺义区| 松原市| 赤峰市| 沁水县| 游戏| 铜川市| 井陉县| 敦煌市| 江陵县| 虎林市| 额济纳旗| 宁陕县| 普兰县| 手机| 中方县| 左云县| 巴东县| 张家川| 醴陵市| 岗巴县| 锡林浩特市| 屏山县| 阿鲁科尔沁旗| 新竹县| 房产| 南漳县| 平利县| 册亨县| 饶阳县| 讷河市|