Hydroxyapatite (HA) is a well-known and widely used efficient adsorbent for toxic metal ion and radionuclide removal from wastewater. However, the relationship between the structural parameters of HA and its adsorption characteristics (capacity, selectivity, kinetic parameters) requires in-depth study. In this study, HA with different crystalline and porous structures was obtained using crystallisation inhibitors of different natures, and their adsorption properties in a multicomponent solution (Cd²⁺, Co²⁺, Cu²⁺, Fe³⁺, Ni²⁺, Pb²⁺ and Zn²⁺) was investigated. Using low doses of inhibitors (Mg²⁺ ions and hydroxyethylenediphosphonic acid) had a positive effect on HA adsorption characteristics, due to their low degree of crystallinity (amorphous calcium phosphate) and a well-developed porous structure (A_BET up to 200-240?m²?g^?1). The adsorption capacity of the HA samples in relation to the Cd²⁺, Cu²⁺, Fe³⁺, Pb²⁺, Zn²⁺ions and their simultaneous presence in the solution varied from 0.13 to 1.28?mmol g^?1. The achieved residual concentration of Pb²⁺, Zn²⁺ and Cu²⁺ions was below the maximum concentration limit, and the ions of Fe³⁺ were almost equal to zero. The highest adsorption of Co²⁺ and Ni²⁺ ions was observed for HA obtained in the presence of Mg²⁺. HA prepared with HEPD has been shown to have the highest efficiency towards Cd²⁺, Cu²⁺, Fe³⁺, Pb²⁺, Zn²⁺ ions. The adsorption kinetic data fitted well with the pseudo-second-order model. It was shown that, depending on the composition and structural characteristics of the prepared HA, ion-exchange and dissolution-precipitation were the two main mechanisms in their interaction with metal ions.