一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

ChemicalBook >> journal list >> Advanced Synthesis & Catalysis >>article
Advanced Synthesis & Catalysis

Advanced Synthesis & Catalysis

IF: 4.4
Download PDF

Reagent-Controlled Chemodivergent Approach to Thiazolines and Thiazines from α-N-Hydroxyimino Dithioesters

Published:9 August 2022 DOI: 10.1002/adsc.202200511
Subhasish Ray, Saurabh Singh, Ganesh Kumar, Gaurav Shukla, Maya Shankar Singh

Abstract

A chemoselective route to thiazolines and thiazines has been devised by heterocyclization of viable α-N-hydroxyimino-β-oxodithioesters with 2-chloroethylamine hydrochloride/3-chloropropylamine hydrochloride, which does not require metals or additives and proceeds at 0–60?°C. The overall transformation involves base mediated intramolecular cyclization of α-N-hydroxyimino-β-oxodithioesters to 4-membered oxazete-4-thione intermediates followed by coupling with chloroalkyl amines via tandem ring cleavage and C?N/C?S bonds formation enabling the construction of thiazolines/thiazines in one-pot. This strategy allows broadening the arsenal of synthetic methods to obtain N,S-heterocycles utilizing substrates prepared according to reported procedures.

Substances (4)

Related products
Procduct Name CAS Molecular Formula Supplier Price
2-Chloroethylamine hydrochloride 870-24-6 C2H7Cl2N 602 suppliers $4.00-$1732.50
3-Chloropropylamine hydrochloride 6276-54-6 C3H9Cl2N 443 suppliers $5.00-$7009.70
3-chloropropylamine 14753-26-5 C3H8ClN 19 suppliers Inquiry
2-Chloroethylamine Hydrochloride 1818218-85-7 C10H9NO2 1 suppliers Inquiry

Similar articles

IF:0

A parallel approach to direct resolution of albuterol

Chinese Science Bulletin Q. Zhong,?Xiaohua Peng,etc Published: 9 September 2010
IF:2.5

N,N-diethylhydroxylamine: A new electron donor to photosystem II

Biochemical and biophysical research communications S.C. Sabat, T.Sudhakar Babu,etc Published: 16 September 1991
IF:3.3

Weinreb Amide Approach to the Practical Synthesis of a Key Remdesivir Intermediate

The Journal of Organic Chemistry Yuanchao Xie, Tianwen Hu,etc Published: 18 March 2021
江阴市| 虎林市| 威信县| 花莲县| 松滋市| 库车县| 佛山市| 湄潭县| 铜川市| 花莲市| 河北区| 天镇县| 哈巴河县| 九龙坡区| 芦山县| 潼南县| 舞阳县| 临海市| 嘉定区| 航空| 新源县| 合水县| 昭觉县| 电白县| 垫江县| 安溪县| 内丘县| 彭山县| 祁东县| 图们市| 太仓市| 玛多县| 德令哈市| 九龙坡区| 富阳市| 大姚县| 琼海市| 隆化县| 永州市| 垦利县| 林周县|